公开(公告)号：EP2938612A1

公开(公告)日：2015-11-04

申请号：EP13814998.4

申请日：2013-12-30

申请人： OriBase Pharma

发明人： CHEVE, Gwénaël ,  DAYDE-CAZALS, Bénédicte ,  FAUVEL, Bénédicte ,  BORIES, Cédric ,  YASRI, Abdelaziz

IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P35/00

CPC分类号： C07D471/04 ,  A61K31/437 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/158 ,  G01N33/5023 ,  G01N33/573 ,  G01N2333/912

摘要： The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.

摘要翻译： 本发明涉及下式（I）的化合物和/或其药学上可接受的加成盐，溶剂合物，对映异构体，非对映异构体，以及它们的混合物。 因此，本发明的主题还包括式（I）化合物的制备，其用途，特别是抑制涉及例如许多疾病例如癌症或免疫系统疾病的蛋白激酶。

公开(公告)号：EP2938614A1

公开(公告)日：2015-11-04

申请号：EP13815532.0

申请日：2013-12-30

申请人： OriBase Pharma

发明人： CHEVE, Gwénaël ,  DAYDE-CAZALS, Bénédicte ,  FAUVEL,Bénédicte ,  BORIES, Cédric ,  YASRI, Abdelaziz

IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P35/00 ,  A61P37/00 ,  A61P29/00 ,  A61P25/28 ,  A61P19/00 ,  A61P7/02

CPC分类号： C07D471/04 ,  G01N33/574 ,  G01N33/57484 ,  G01N2333/912 ,  G01N2500/10 ,  G01N2800/52

摘要： The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.

摘要翻译： 本发明涉及下式（I）化合物和/或其药学上可接受的加成盐，溶剂合物，对映异构体，非对映异构体，以及它们的混合物。 因此，本发明的主题还包括式（I）化合物的制备，其用途，特别是抑制例如涉及许多疾病如癌症或免疫系统疾病的蛋白激酶。

公开(公告)号：EP2938613A1

公开(公告)日：2015-11-04

申请号：EP13814999.2

申请日：2013-12-30

申请人： OriBase Pharma

发明人： CHEVE, Gwénaël ,  DAYDE-CAZALS, Bénédicte ,  FAUVEL, Bénédicte ,  BORIES, Cédric ,  YASRI, Abdelaziz

IPC分类号： C07D471/04 ,  A61K31/4375 ,  A61P35/02 ,  A61P35/00

CPC分类号： C07D471/04 ,  A61K31/4375 ,  C12Q1/485 ,  G01N33/57484 ,  G01N2333/91215 ,  G01N2500/04 ,  G01N2500/10 ,  G01N2500/20 ,  G01N2800/52

摘要： The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.