公开(公告)号：EP0953843A3

公开(公告)日：2000-09-06

申请号：EP99303195.4

申请日：1999-04-26

申请人： Ortho-Clinical Diagnostics, Inc.

发明人： Brookes, Ronald F. ,  Jacobs, Merrit N. ,  Lowne, Alan J. ,  Shaw, James D.

IPC分类号： G01N35/10

CPC分类号： G01N35/1016 ,  G01N2035/1025 ,  Y10T436/119163

摘要： A method and apparatus for detecting improper liquid content of a metering tip of an analyzer. The method detects the content or status using radiation between 630 and 2000 nm, and comprises the steps of: a) aspirating the liquid into one of the tips to fill the tip to a nominal level; b) scanning the liquid in the tip by a scanner (16) comprising a light source (18) and a light detector (26), the source and detector being aligned along a direction that is generally normal to the tip axis; c) providing relative motion between the tip and the scanner while the step b) is conducted, so that the scanner scans from a first position below the tip where a pendant drop of the aqueous liquid would be located if present, to a predetermined second position above the first position that represents the nominal level; d) while conducting steps b) and c), separately detecting at each of several portions of the tip between and including the first and second positions, the amount of light transmitted to the detector, so that all liquid-containing levels within the tip are detected; e) comparing the detected light of step d) with light known to be transmitted if liquid is present only at all of the levels, free of air bubbles; and f) flagging the results as being in error if water is detected at the first position; or if it is not detected because of air bubbles at any one of the levels within the tip up to and including the second position; or if it is detected above the second position.

摘要翻译： 一种用于检测分析仪的计量尖端的不适当液体含量的方法和装置。 该方法使用630和2000nm之间的辐射来检测内容或状态，并且包括以下步骤：a）将液体吸入其中一个尖端以将尖端填充到标称水平; b）通过包括光源（18）和光检测器（26）的扫描器（16）扫描尖端中的液体，源和检测器沿着与尖端轴线大致正交的方向对齐; c）在步骤b）进行时，在尖端和扫描仪之间提供相对运动，使得扫描仪从位于下方的第一位置扫描水中液体的悬垂液滴的位置（如果存在）到预定的第二位置 高于名义水平的第一位; d）在执行步骤b）和c）时，分别检测在第一和第二位置之间的包括第一和第二位置的尖端的几个部分的每一个处，传输到检测器的光量，使得尖端内的所有含液体水平为 检测; e）将步骤d）的检测光与已知要传输的光进行比较，如果液体仅在没有气泡的所有水平下存在; 以及f）如果在第一位置检测到水，则将结果标记为错误; 或者如果由于气泡在尖端内的任何一个水平直到并包括第二位置而没有被检测到; 或者如果它被检测到高于第二位置。

公开(公告)号：EP0953843B1

公开(公告)日：2003-12-10

申请号：EP99303195.4

申请日：1999-04-26

申请人： Ortho-Clinical Diagnostics, Inc.

发明人： Brookes, Ronald F. ,  Jacobs, Merrit N. ,  Lowne, Alan J. ,  Shaw, James D.

IPC分类号： G01N35/10

CPC分类号： G01N35/1016 ,  G01N2035/1025 ,  Y10T436/119163

公开(公告)号：EP0953843A2

公开(公告)日：1999-11-03

申请号：EP99303195.4

申请日：1999-04-26

申请人： Ortho-Clinical Diagnostics, Inc.

发明人： Brookes, Ronald F. ,  Jacobs, Merrit N. ,  Lowne, Alan J. ,  Shaw, James D.

IPC分类号： G01N35/10

CPC分类号： G01N35/1016 ,  G01N2035/1025 ,  Y10T436/119163

摘要： A method and apparatus for detecting improper liquid content of a metering tip of an analyzer. The method detects the content or status using radiation between 630 and 2000 nm, and comprises the steps of:

a) aspirating the liquid into one of the tips to fill the tip to a nominal level;
b) scanning the liquid in the tip by a scanner (16) comprising a light source (18) and a light detector (26), the source and detector being aligned along a direction that is generally normal to the tip axis;
c) providing relative motion between the tip and the scanner while the step b) is conducted, so that the scanner scans from a first position below the tip where a pendant drop of the aqueous liquid would be located if present, to a predetermined second position above the first position that represents the nominal level;
d) while conducting steps b) and c), separately detecting at each of several portions of the tip between and including the first and second positions, the amount of light transmitted to the detector, so that all liquid-containing levels within the tip are detected;
e) comparing the detected light of step d) with light known to be transmitted if liquid is present only at all of the levels, free of air bubbles; and
f) flagging the results as being in error if water is detected at the first position; or if it is not detected because of air bubbles at any one of the levels within the tip up to and including the second position; or if it is detected above the second position.

摘要翻译： 一种用于检测分析仪的计量尖端的不适当液体含量的方法和装置。 该方法使用630和2000nm之间的辐射来检测内容或状态，并且包括以下步骤：a）将液体吸入其中一个尖端以将尖端填充到标称水平; b）通过包括光源（18）和光检测器（26）的扫描器（16）扫描尖端中的液体，源和检测器沿着与尖端轴线大致正交的方向对齐; c）在步骤b）进行时，在尖端和扫描仪之间提供相对运动，使得扫描仪从位于下方的第一位置扫描水中液体的悬垂液滴的位置（如果存在）到预定的第二位置 高于名义水平的第一位; d）在执行步骤b）和c）时，分别检测在第一和第二位置之间的包括第一和第二位置的尖端的几个部分的每一个处，传输到检测器的光量，使得尖端内的所有含液体水平为 检测; e）将步骤d）的检测光与已知要传输的光进行比较，如果液体仅在没有气泡的所有水平下存在; 以及f）如果在第一位置检测到水，则将结果标记为错误; 或者如果由于气泡在尖端内的任何一个水平直到并包括第二位置而没有被检测到; 或者如果它被检测到高于第二位置。