利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

439 条记录 (耗时 0.03 秒)

    ASSAY DEVICE HAVING UNIFORM FLOW AROUND CORNERS
    7.
    发明授权
    ASSAY DEVICE HAVING UNIFORM FLOW AROUND CORNERS 有权

    公开(公告)号：EP3088892B1

    公开(公告)日：2018-07-25

    申请号：EP16174438.8

    申请日：2013-01-18

    申请人： Ortho-Clinical Diagnostics, Inc.

    发明人： KANALEY, James D. ,  DING, Zhong ,  HOSIMER, Philip C. ,  SCALICE, Edward R. ,  DANIELSON, Susan ,  TOMASSO, David A. ,  WARREN, Timothy C.

    IPC分类号： G01N33/543 ,  B01L3/00

    CPC分类号： G01N33/54366 ,  B01L3/5023 ,  B01L3/502746 ,  B01L2200/0636 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2400/086 ,  G01N1/28 ,  Y10T436/2575

    摘要： An assay device includes: a liquid sample zone; a reagent zone downstream and in fluid communication with the sample zone containing a reagent material; a detection zone in fluid communication with the reagent zone having capture elements bound thereto; and a wicking zone in fluid communication with the capture zone having a capacity to receive liquid sample flowing from the detection zone. The sample receiving zone, the reagent zone, the detection zone and the wicking zone define a fluid flow path and at least a part of the fluid flow path has a substrate and projections which extend substantially vertically from the substrate, wherein the projections have a height, cross-section and a distance between one another that defines a space between the projections capable of generating capillary flow parallel to the substrate surface. In addition, the fluid flow path having projections includes a corner section which changes the direction of the flow path. The projections in or around the corner section are modified to maintain the configuration of the flow front of the sample flowing through the flow path after the corner is substantially the same configuration as before the corner.

    Reagent zone deposition pattern
    8.
    发明授权
    Reagent zone deposition pattern 有权

    公开(公告)号：EP2781920B1

    公开(公告)日：2018-06-20

    申请号：EP14154484.1

    申请日：2014-02-10

    申请人： ORTHO-CLINICAL DIAGNOSTICS, INC.

    发明人： Ding, Zhong

    IPC分类号： G01N33/543 ,  B01L3/00 ,  G01N33/558

    CPC分类号： G01N33/54393 ,  B01L3/5023 ,  B01L3/502746 ,  B01L2200/0621 ,  B01L2200/0636 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/086 ,  G01N33/54386 ,  G01N33/558

    摘要： An assay device includes: a liquid sample addition zone; a reagent zone downstream and in fluid communication with the sample zone that includes a reagent cell having a line of symmetry in the direction of fluid flow; a reagent material in the reagent cell, wherein the reagent material includes a first reagent material located at the axis of symmetry and is left-right symmetric, and a second and third reagent material having a substantially identical shape and volume and located in mirror locations from the line of symmetry; a detection zone in fluid communication with the reagent zone; and a wicking zone in fluid communication with the detection zone having a capacity to receive liquid sample flowing from the detection zone. The liquid sample addition zone, the detection zone and the wicking zone define a fluid flow path.

    LATERAL-FLOW ASSAY DEVICE HAVING FLOW CONSTRICTIONS
    9.
    发明授权
    LATERAL-FLOW ASSAY DEVICE HAVING FLOW CONSTRICTIONS 有权

    公开(公告)号：EP3177926B1

    公开(公告)日：2018-06-06

    申请号：EP15750889.6

    申请日：2015-08-05

    申请人： Ortho-Clinical Diagnostics, Inc.

    发明人： DING, Zhong ,  SCALICE, Edward R. ,  SALOTTO, Daniel P.

    IPC分类号： G01N33/543

    CPC分类号： B01L3/5023 ,  B01L2300/041 ,  B01L2300/0867 ,  B01L2300/161 ,  B01L2400/0406 ,  G01N33/54386

    摘要： A lateral-flow assay device includes a substrate having a sample addition zone and a wash addition zone downstream thereof along a fluid flow path through which a sample flows. The fluid flow path is configured to receive a wash fluid in the wash addition zone. A hydrophilic surface is arranged in the wash addition zone. Flow constriction(s) are spaced apart from the fluid flow path and arranged to define, with the hydrophilic surface, a reservoir configured to retain the wash fluid by formation of a meniscus between the hydrophilic surface and the flow constriction(s). The fluid flow path draws the wash fluid from the reservoir by capillary pressure. Apparatus for analyzing a fluidic sample and methods of displacing a fluidic sample in a fluid flow path of an assay device are also described.