公开(公告)号：EP3613499A1

公开(公告)日：2020-02-26

申请号：EP19203649.9

申请日：2013-10-23

申请人： Oxford Nanopore Technologies Limited

发明人： HYDE, Jason Robert ,  BAHAMON, Pedro Miguel Ortiz ,  BROWN, Andrew John ,  HERON, Andrew John ,  MACKETT, Paul Raymond

IPC分类号： B01J19/00 ,  B01L3/00 ,  G01N33/487

摘要： An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.

公开(公告)号：EP3206794A1

公开(公告)日：2017-08-23

申请号：EP15784125.5

申请日：2015-10-15

申请人： Oxford Nanopore Technologies Limited

发明人： BROWN, Clive Gavin ,  HYDE, Jason Robert ,  JACKSON, Mark David ,  MACKETT, Paul Raymond ,  MCKENDRY, Jonathan Edward ,  WILTSHIRE, Richard Kenneth John

IPC分类号： B01L3/00 ,  G01N33/487 ,  G01R31/28 ,  H01R3/08 ,  H01R13/02

CPC分类号： B01L3/502715 ,  B01L3/50857 ,  B01L2200/025 ,  B01L2200/04 ,  B01L2200/12 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0819 ,  B01L2300/161 ,  G01N33/48721 ,  H01R3/08 ,  H01R13/02

摘要： A detachable electrical device can be formed from a kit comprising a pair of component parts adapted for connection to each other, wherein the connected components of the device may be subsequently disconnected, comprising: an array of electrical connectors, each electrical connector comprising an electrically conductive liquid; and an array of electrodes; wherein the arrays can be brought into contact with each other so as to provide a plurality of electrical connections between the electrically conductive liquid of the array of electrical connectors and the electrodes of the array of electrodes, and wherein the electrical connections may be subsequently broken by detaching the electrically conductive liquid from the electrodes of the array.

摘要翻译： 可拆卸电气装置可以由套件形成，所述套件包括适于彼此连接的一对部件部分，其中所述装置的连接部件随后可以被断开，包括：电连接器阵列，每个电连接器包括导电的 液体; 和电极阵列; 其中阵列可以彼此接触以提供电连接器阵列的导电液体与电极阵列的电极之间的多个电连接，并且其中电连接随后可以被 从阵列的电极分离导电液体。

公开(公告)号：EP3206794B1

公开(公告)日：2019-08-07

申请号：EP15784125.5

申请日：2015-10-15

申请人： Oxford Nanopore Technologies Limited

发明人： BROWN, Clive Gavin ,  HYDE, Jason Robert ,  JACKSON, Mark David ,  MACKETT, Paul Raymond ,  MCKENDRY, Jonathan Edward ,  WILTSHIRE, Richard Kenneth John

IPC分类号： B01L3/00 ,  G01R31/44 ,  G01N33/487

公开(公告)号：EP2911781B1

公开(公告)日：2019-12-18

申请号：EP13785899.9

申请日：2013-10-23

申请人： Oxford Nanopore Technologies Limited

发明人： HYDE, Jason Robert ,  BAHAMON, Pedro Miguel Ortiz ,  BROWN, Clive Gavin ,  HERON, Andrew John ,  MACKETT, Paul Raymond

IPC分类号： B01J19/00 ,  B01L3/00 ,  G01N33/487

公开(公告)号：EP2911781A2

公开(公告)日：2015-09-02

申请号：EP13785899.9

申请日：2013-10-23

申请人： Oxford Nanopore Technologies Limited

发明人： HYDE, Jason Robert ,  BAHAMON, Pedro Miguel Ortiz ,  BROWN, Clive Gavin ,  HERON, Andrew John ,  MACKETT, Paul Raymond

IPC分类号： B01J19/00 ,  B01L3/00 ,  G01N33/487

摘要： An array of membranes comprising amphipathic molecules is formed using an apparatus comprising a support defining an array of compartments. Volumes comprising polar medium are provided within respective compartments and a layer comprising apolar medium is provided extending across the openings with the volumes. Polar medium is flowed across the support to displace apolar medium and form a layer in contact with the volumes, forming membranes comprising amphipathic molecules at the interfaces. In one construction of the apparatus, the support that comprises partitions which comprise inner portions and outer portions. The inner portions define inner recesses without gaps therebetween that are capable of constraining the volumes comprising polar medium contained in neighbouring inner recesses from contacting each other. The outer portions extend outwardly from the inner portions and have gaps allowing the flow of an apolar medium across the substrate.