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1.发明授权AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT 有权阿明衍生物，工艺及其使用作为抗真菌剂及其
公开(公告)号：EP1561744B1
公开(公告)日：2007-04-18
申请号：EP05009223.8
申请日：1998-08-05
发明人： Itoh, Takao c/o Pola Chemical Industries Inc. , Nakashima, Takuji c/o Pola Chemical Ind. Inc. , Nozawa, Akira c/o Pola Chemical Industries Inc. , Yokoyama, Kouji c/o Pola Chemical Industries Inc. , Takimoto, Hiroyuki c/o Pola Chemical Ind. Inc. , Yuasa, Masayuki c/o Pola Chemical Industries Inc. , Kawazu, Yukio c/o Pola Chemical Industries Inc. , Suzuki, Toshimitsu c/o Pola Chemical Ind. Inc. , Majima, Toshiro c/o Pola Chemical Industries Inc.
IPC分类号： C07C211/26 , C07C209/68 , A61K31/135
CPC分类号： C07D295/135 , C07C211/26 , C07C211/28 , C07C211/29 , C07C211/49 , C07C215/52 , C07C217/60 , C07C225/16 , C07C229/38 , C07C255/58 , C07C2601/02 , C07F7/1852 , C07F7/1856
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2.发明公开AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT 有权胺衍生物，其制备方法及其作为抗菌剂的用途
公开(公告)号：EP1561744A3
公开(公告)日：2005-08-24
申请号：EP05009223.8
申请日：1998-08-05
发明人： Itoh, Takao c/o Pola Chemical Industries Inc. , Nakashima, Takuji c/o Pola Chemical Ind. Inc. , Nozawa, Akira c/o Pola Chemical Industries Inc. , Yokoyama, Kouji c/o Pola Chemical Industries Inc. , Takimoto, Hiroyuki c/o Pola Chemical Ind. Inc. , Yuasa, Masayuki c/o Pola Chemical Industries Inc. , Kawazu, Yukio c/o Pola Chemical Industries Inc. , Suzuki, Toshimitsu c/o Pola Chemical Ind. Inc. , Majima, Toshiro c/o Pola Chemical Industries Inc.
IPC分类号： C07C211/26 , C07C209/68 , C07C225/04 , C07C221/00 , A61K31/135
CPC分类号： C07D295/135 , C07C211/26 , C07C211/28 , C07C211/29 , C07C211/49 , C07C215/52 , C07C217/60 , C07C225/16 , C07C229/38 , C07C255/58 , C07C2601/02 , C07F7/1852 , C07F7/1856
摘要： Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below or salts thereof are provided. [in the formula (1), R 1 represents a C 1-5 alkyl group which may be halogenated, R 2 represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-1-phenylethyl)benzyl group, or 1- or 2- naphthylmethyl group; R 3 represents oxygen atom or a methylene group which may be substituted by a C 1-4 alkyl group; and R 4 represents 1- or 2 naphthyl group or a phenyl group which may be substituted.
摘要翻译： 提供了由以下通式（1）表示的具有优异抗真菌效果的新型胺衍生物或其盐。 [式（1）中，R 1表示可以被卤代的C 1-5烷基，R 2表示4-（1,1-二甲基烷基）苄基，4-（1-甲基-1-苯乙基）苄基或 1-或2-萘甲基; R3代表氧原子或可被C1-4烷基取代的亚甲基; R4代表1或2个萘基或可被取代的苯基。
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3.发明公开Amine derivatives, process for producing the same and their use as antimycotic agent 有权阿明衍生物，工艺及其使用作为抗真菌剂及其
公开(公告)号：EP1561744A2
公开(公告)日：2005-08-10
申请号：EP05009223.8
申请日：1998-08-05
发明人： Itoh, Takao c/o Pola Chemical Industries Inc. , Nakashima, Takuji c/o Pola Chemical Ind. Inc. , Nozawa, Akira c/o Pola Chemical Industries Inc. , Yokoyama, Kouji c/o Pola Chemical Industries Inc. , Takimoto, Hiroyuki c/o Pola Chemical Ind. Inc. , Yuasa, Masayuki c/o Pola Chemical Industries Inc. , Kawazu, Yukio c/o Pola Chemical Industries Inc. , Suzuki, Toshimitsu c/o Pola Chemical Ind. Inc. , Majima, Toshiro c/o Pola Chemical Industries Inc.
IPC分类号： C07C211/26 , C07C209/68 , C07C225/04 , C07C221/00 , A61K31/135
CPC分类号： C07D295/135 , C07C211/26 , C07C211/28 , C07C211/29 , C07C211/49 , C07C215/52 , C07C217/60 , C07C225/16 , C07C229/38 , C07C255/58 , C07C2601/02 , C07F7/1852 , C07F7/1856
摘要： Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below or salts thereof are provided.
[in the formula (1), R 1 represents a C 1-5 alkyl group which may be halogenated, R 2 represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-1-phenylethyl)benzyl group, or 1- or 2- naphthylmethyl group; R 3 represents oxygen atom or a methylene group which may be substituted by a C 1-4 alkyl group; and R 4 represents 1- or 2 naphthyl group or a phenyl group which may be substituted.摘要翻译： 它们提供了具有下面的通式（1）表示的抗真菌优良效果新的胺衍生物或其盐。
A在式（1）中，R <1> darstellt C1-5烷基可被卤代，R <2> darstellt 4-（1,1-二甲基烷基）苄基，4-（1-甲基 1-苯乙基）苄基，或1-或2-萘基甲基; [R <3> darstellt氧原子或可被C 1-4烷基被substituiertem亚甲基; 且R <4> darstellt 1-或2-萘基或可被substituiertem苯基。
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