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公开(公告)号：EP2812004B1
公开(公告)日：2018-06-27
申请号：EP13747100.9
申请日：2013-02-08
发明人： QI, Hongyan , CHOI, Soongyu , DAKKA, Amal , KARP, Gary, Mitchell , NARASIMHAN, Jana , NARYSHKIN, Nikolai , TURPOFF, Anthony, A. , WEETALL, Marla, L. , WELCH, Ellen , WOLL, Matthew, G. , YANG, Tianle , ZHANG, Nanjing , ZHANG, Xiaoyan , ZHAO, Xin , GREEN, Luke , PINARD, Emmanuel , RATNI, Hasane
IPC分类号： A61K31/53 , A61K31/519 , C07D471/04 , C07D487/04 , C07D519/00 , A61K31/4375 , A61P25/00
CPC分类号： C07D471/04 , A61K31/519 , C07D239/70 , C07D487/04 , C07D519/00
摘要： Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy.
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公开(公告)号：EP2812004A2
公开(公告)日：2014-12-17
申请号：EP13747100.9
申请日：2013-02-08
发明人： QI, Hongyan , CHOI, Soongyu , DAKKA, Amal , KARP, Gary, Mitchell , NARASIMHAN, Jana , NARYSHKIN, Nikolai , TURPOFF, Anthony, A. , WEETALL, Marla, L. , WELCH, Ellen , WOLL, Matthew, G. , YANG, Tianle , ZHANG, Nanjing , ZHANG, Xiaoyan , ZHAO, Xin , GREEN, Luke , PINARD, Emmanuel , RATNI, Hasane
IPC分类号： A61K31/53 , A01N43/90 , A61K31/519 , C07D239/70
CPC分类号： C07D471/04 , A61K31/519 , C07D239/70 , C07D487/04 , C07D519/00
摘要： Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy.
摘要翻译： 本文提供了化合物，其组合物以及用于治疗脊髓性肌萎缩的用途。
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公开(公告)号：EP3406252A1
公开(公告)日：2018-11-28
申请号：EP18179491.8
申请日：2013-02-08
发明人： QI, Hongyan , CHOI, Soongyu , DAKKA, Amal , KARP, Gary, Mitchell , NARASIMHAN, Jana , NARYSHKIN, Nikolai A. , TURPOFF, Anthony, A. , WEETALL, Marla, L. , WELCH, Ellen , WOLL, Matthew, G. , YANG, Tianle , ZHANG, Nanjing , ZHANG, Xiaoyan , ZHAO, Xin , GREEN, Luke , PINARD, Emmanuel , RATNI, Hasane
IPC分类号： A61K31/53 , A61K31/519 , C07D471/04 , C07D487/04 , C07D519/00 , A61K31/4375 , A61P25/00
摘要： Provided herein are compounds of formula (IIa1), compositions thereof and uses therewith for treating spinal muscular atrophy.
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公开(公告)号：EP3406252B1
公开(公告)日：2020-05-13
申请号：EP18179491.8
申请日：2013-02-08
发明人： QI, Hongyan , CHOI, Soongyu , DAKKA, Amal , KARP, Gary, Mitchell , NARASIMHAN, Jana , NARYSHKIN, Nikolai A. , TURPOFF, Anthony, A. , WEETALL, Marla, L. , WELCH, Ellen , WOLL, Matthew, G. , YANG, Tianle , ZHANG, Nanjing , ZHANG, Xiaoyan , ZHAO, Xin , GREEN, Luke , PINARD, Emmanuel , RATNI, Hasane
IPC分类号： A61K31/53 , A61K31/519 , C07D471/04 , C07D487/04 , C07D519/00 , A61K31/4375 , A61P25/00
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公开(公告)号：EP4377317A1
公开(公告)日：2024-06-05
申请号：EP22761694.3
申请日：2022-07-29
发明人： BABU, Suresh , ALAM, Rauful , BHATTACHARYYA, Anuradha , CHEN, Guangming , EASTWOOD, Matthew, S. , HOSSEYNI, Seyedmorteza , JIANG, Yao , KARP, Gary, Mitchell , MOON, Young-choon , NARASIMHAN, Jana , REN, Hongyu , SYDORENKO, Nadiya , WOLL, Matthew, G. , ZHANG, Nanjing
IPC分类号： C07D487/04 , A61P25/14 , A61P25/28 , A61K31/5025
CPC分类号： C07D487/04 , A61P25/14 , A61P25/28
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公开(公告)号：EP4132923A1
公开(公告)日：2023-02-15
申请号：EP21722671.1
申请日：2021-04-08
发明人： SYDORENKO, Nadiya , ALAM, Rauful , BABU, Suresh , BHATTACHARYYA, Anuradha , CHEN, Guangming , CHIERCHIA, Matteo , KARP, Gary, Mitchell , LUONG, Tom, Tuan , MAZZOTTI, Anthony, R. , MOON, Young-Choon , MSZAR, Nicholas, Walter , NARASIMHAN, Jana , PATEL, Jigar, S. , REN, Hongyu , WANG, Gang , WOLL, Matthew, G. , ZHANG, Nanjing , ZHANG, Xiaoyan
IPC分类号： C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D498/04 , C07D513/04 , A61K31/53 , A61P25/28
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公开(公告)号：EP3773552A1
公开(公告)日：2021-02-17
申请号：EP19777730.3
申请日：2019-03-27
发明人： SYDORENKO, Nadiya , ALAM, Md, Rauful , AMEDZO, Lukiana , BABU, Suresh , BAIAZITOV, Ramil, Y. , BARRAZA, Scott, J. , BHATTACHARYYA, Anuradha , KARP, Gary, Mitchell , KENTON, Nathaniel, T. , MAZZOTTI, Anthony, R. , MOON, Young-Choon , MSZAR, Nicholas, W. , NARASIMHAN, Jana , PAL, Sudipta , PATEL, Jigar, S. , TURPOFF, Anthony , WOLL, Matthew, G. , XU, Zhenrong , ZHANG, Nanjing
IPC分类号： A61K31/395 , A61K31/53 , A61K47/10 , C07D251/12 , C07D251/16 , C07D401/02
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公开(公告)号：EP3924050A1
公开(公告)日：2021-12-22
申请号：EP20714316.5
申请日：2020-02-10
发明人： WANG, Jiashi , ARNOLD, Michael, A. , DAKKA, Amal , KARP, Gary, Mitchell , NARASIMHAN, Jana , NARYSHKIN, Nikolai, A. , ZHANG, Nanjing
IPC分类号： A61P25/00 , C07D487/04 , A61K31/519
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9.发明授权1,2,4-OXADIAZOLE BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE 有权1,2,4-OXADIAZOLBENZOESÄUREVERBINDUNGEN和它们在义抑制和治疗疾病的
公开(公告)号：EP1618098B1
公开(公告)日：2014-11-19
申请号：EP04759404.9
申请日：2004-04-09
发明人： KARP, Gary, Mitchell , HWANG, Seongwoo , CHEN, Guangming , ALMSTEAD, Neil, Gregory , MOON, Young-Choon
IPC分类号： C07D271/06 , A61P35/00 , A61K31/4245
CPC分类号： A61K31/4245 , A61K9/0053 , A61K9/12 , A61K9/48 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/5377 , A61K31/655 , A61K45/06 , A61P27/02 , C07D271/06 , C07D271/12 , C07D285/14 , C07D413/02 , C07D413/04 , C07D413/10
摘要： The present invention relates to a compound 3-[5-(2-Fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid, having the structure: or a pharmaceutically acceptable salt thereof. The present invention also relates to a pharmaceutical composition and a single unit dosage thereof, as well as the said compound for use in a method of treating, preventing or ameliorating diseases as defined herein.
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公开(公告)号：EP4072677A1
公开(公告)日：2022-10-19
申请号：EP20829474.4
申请日：2020-12-07
发明人： ZHANG, Nanjing , ARNOLD, Michael, A. , DAKKA, Amal , KARP, Gary, Mitchell , LUONG, Tom, Tuan , MORRILL, Christie , NARASIMHAN, Jana , NARYSHKIN, Nikolai, A. , TURPOFF, Anthony , WANG, Jiashi , ZHANG, Xiaoyan
IPC分类号： A61P25/00 , C07D495/04 , A61K31/519
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