公开(公告)号：EP1516866A9

公开(公告)日：2005-10-05

申请号：EP03712147.2

申请日：2003-04-03

申请人： PULEVA BIOTECH, S.A.

发明人： GEERLINGS, Arjan ,  LOPEZ-HUERTAS Leon, Eduardo ,  MORALES SANCHEZ, Juan Carlos ,  BOZA PUERTA, Julio ,  JIMENEZ LOPEZ, Jesus

IPC分类号： C07C69/025 ,  C07C69/16 ,  A61K31/222 ,  A61K7/42 ,  A61P9/00 ,  A61P1/16 ,  A61P13/00 ,  A61P3/10 ,  A61P29/00

CPC分类号： A23C9/13 ,  A23C9/152 ,  A23C15/12 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/2131 ,  A61K8/37 ,  A61Q17/04 ,  C07C69/007 ,  C07C69/017 ,  C07C69/28 ,  C07C69/30 ,  C07C69/533 ,  C07C69/58 ,  C07C69/587 ,  A23V2200/326 ,  A23V2250/2132

摘要： The present invention refers to the use of phenolic compounds and their derivatives represented by formula I wherein R 1 and R 2 are selected from among: OH, OCOalkyl, or OCOalkenyl, and R 3 is either H, OH, OCOalkyl or OCOalkenyl, wherein the alkyl or alkenyl chains present from 2 to 22 carbon atoms and wherein at least one OCOalkyl or OCOalkenyl group is present in the structure, for the prevention and treatment of cardiovascular, hepatic or renal diseases, as well as to their cosmetic applications, to compositions that include these compounds and to some novel phenolic compounds and derivatives.

公开(公告)号：EP1516866A1

公开(公告)日：2005-03-23

申请号：EP03712147.2

申请日：2003-04-03

申请人： PULEVA BIOTECH, S.A.

发明人： GEERLINGS, Arjan ,  LOPEZ-HUERTAS Leon, Eduardo ,  MORALES SANCHEZ, Juan Carlos ,  BOZA PUERTA, Julio ,  JIMENEZ LOPEZ, Jesus

IPC分类号： C07C69/025 ,  C07C69/16 ,  A61K31/222 ,  A61K7/42 ,  A61P9/00 ,  A61P1/16 ,  A61P13/00 ,  A61P3/10 ,  A61P29/00

CPC分类号： A23C9/13 ,  A23C9/152 ,  A23C15/12 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/2131 ,  A61K8/37 ,  A61Q17/04 ,  C07C69/007 ,  C07C69/017 ,  C07C69/28 ,  C07C69/30 ,  C07C69/533 ,  C07C69/58 ,  C07C69/587 ,  A23V2200/326 ,  A23V2250/2132

摘要： The present invention refers to the use of phenolic compounds and their derivatives represented by formula I wherein R 1 and R 2 are selected from among: OH, OCOalkyl, or OCOalkenyl, and R 3 is either H, OH, OCOalkyl or OCOalkenyl, wherein the alkyl or alkenyl chains present from 2 to 22 carbon atoms and wherein at least one OCOalkyl or OCOalkenyl group is present in the structure, for the prevention and treatment of cardiovascular, hepatic or renal diseases, as well as to their cosmetic applications, to compositions that include these compounds and to some novel phenolic compounds and derivatives.

摘要翻译： 本发明涉及使用由下式表示的酚类化合物和它们的衍生物的我worin R1和R2选自：OH，OCO烷基，或OCOalkenyl，且R 3是H，OH，OCO烷基或OCOalkenyl，worin烷基或链烯 本从2至22个碳原子和worin至少一个OCO烷基或OCOalkenyl基团存在于该结构中，用于心血管，肝或肾疾病，以及作为它们的化妆品应用的预防和治疗，组合物也包括合成的化合物链 和一些新颖的酚类化合物和衍生物。

公开(公告)号：EP1516866B1

公开(公告)日：2006-07-12

申请号：EP03712147.2

申请日：2003-04-03

申请人： PULEVA BIOTECH, S.A.

发明人： GEERLINGS, Arjan ,  LOPEZ-HUERTAS Leon, Eduardo ,  MORALES SANCHEZ, Juan Carlos ,  BOZA PUERTA, Julio ,  JIMENEZ LOPEZ, Jesus

IPC分类号： C07C69/025 ,  C07C69/16 ,  A61K31/222 ,  A61Q17/04 ,  A61P9/00 ,  A61P1/16 ,  A61P13/00 ,  A61P3/10 ,  A61P29/00

CPC分类号： A23C9/13 ,  A23C9/152 ,  A23C15/12 ,  A23L33/105 ,  A23V2002/00 ,  A23V2250/2131 ,  A61K8/37 ,  A61Q17/04 ,  C07C69/007 ,  C07C69/017 ,  C07C69/28 ,  C07C69/30 ,  C07C69/533 ,  C07C69/58 ,  C07C69/587 ,  A23V2200/326 ,  A23V2250/2132

摘要： The invention relates to phenolic compounds and the derivatives thereof which are represented by formula I, wherein: R1 and R2 are selected from OH, OCOalkyl or OCOalkenyl; R3 is H, OH, OCOalkyl or OCOalkenyl; the alkyl or alkenyl chains have between 2 and 22 carbon atoms; and at least one OCOalkyl or OCOalkenyl group is present in the structure. More specifically, the invention relates to the use of said compounds for the prevention or treatment of cardiovascular, hepatic and renal diseases and for cosmetic applications. The invention also relates to compositions containing the above-mentioned compounds and to some novel phenolic compounds and the derivatives thereof.