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公开(公告)号:EP2841583B1
公开(公告)日:2016-04-06
申请号:EP13720846.8
申请日:2013-04-24
申请人: PURAC Biochem BV
CPC分类号: C12P7/56 , B01D21/267 , C12P7/44 , C12P7/46 , C12P7/48 , C12P7/50 , C12P7/52 , Y02P20/582
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公开(公告)号:EP2841583A1
公开(公告)日:2015-03-04
申请号:EP13720846.8
申请日:2013-04-24
申请人: PURAC Biochem BV
CPC分类号: C12P7/56 , B01D21/267 , C12P7/44 , C12P7/46 , C12P7/48 , C12P7/50 , C12P7/52 , Y02P20/582
摘要: The present invention pertains to a fermentation process for the production of an organic acid salt comprising the steps of - fermenting a microorganism in a fermentation medium in a fermentation reactor to form a fermentation broth comprising an organic acid salt, wherein part of the organic acid salt is present in the solid state and part of the organic acid salt is dissolved in the fermentation broth; - withdrawing at least part of the fermentation broth from the fermentation reactor, providing said broth to a hydrocyclone, and withdrawing a top effluent and a bottom effluent from the hydrocyclone; - providing the bottom effluent from the hydocyclone to a solid/liquid separation step, to form a solid fraction and a liquid fraction, - providing at least 30 vol. % of the total of the top effluent from the hydrocyclone and the liquid fraction from the solid-liquid separation step to the fermentation reactor. The process according to the invention is at the same time stable, provides a product with good properties, and provides a high process yield, especially attractive on an industrial scale.
摘要翻译: 本发明涉及一种生产有机酸盐的发酵方法,包括以下步骤:在发酵反应器中的发酵培养基中发酵微生物以形成具有有机酸盐的发酵液,其中部分有机酸盐为 存在于固体状态,部分有机酸盐溶于发酵液中; 从发酵反应器中取出至少部分的发酵肉汤,向水力旋流器提供肉汤,并从水力旋流器中取出顶部流出物和底部流出物; 将底部流出物从水合旋流器提供到固/液分离步骤,以形成固体馏分和液体馏分,提供至少30体积%的来自水力旋流器的顶部流出物和来自固体 - 液体分离步骤到发酵反应器。
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