公开(公告)号：EP2254899A1

公开(公告)日：2010-12-01

申请号：EP09721583.4

申请日：2009-02-13

申请人： Pacific Arrow Limited

发明人： CHAN, Pui-Kwong ,  MAK,May, Sung

IPC分类号： C07H15/24 ,  C07H15/00

CPC分类号： A61K31/7048 ,  A61K31/704 ,  C07H15/24 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/486

摘要： Methods for utilizing the anticancer properties of terpenoid saponin compounds so as to modulate adhesion proteins, inhibit angiogenesis in tumors, modulate gene expression, modulate angiopoietin, enhance an immune response, provide adjuvant activities, provide vaccine activities, or inhibit the metastasis of cancer cells when contacting a subject with the compounds, wherein the cancers compose breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, CNS cancer, melanoma cancer, renal cancer, cervix cancer, esophagus cancer, testis cancer, spleen cancer, kidney cancer, lymph cancer, pancreas cancer, stomach cancer and thyroid cancer Methods, processes, compounds and compositions for antiparasitic applications which include inhibiting leishmaniases, amoebiasis, trypanosomiasis, toxoplasmosis or malaria