公开(公告)号：EP3263684A1

公开(公告)日：2018-01-03

申请号：EP17157314.0

申请日：2017-02-22

Applicant: Pegavision Corporation

Inventor： LAI, Yu-Chin ,  YEH, Min-Tzong ,  CHANG, Han-Yi ,  CHANG, Ya-Hui

IPC: C11D3/00 ,  A61K9/00 ,  A61L12/00 ,  C11D3/22 ,  C11D3/37

CPC classification number: A61L12/14 ,  A61L12/08 ,  A61L12/086 ,  C11D3/0078 ,  C11D3/227 ,  C11D3/3784

Abstract: A solution for treating a contact lens and a contact lens packaging system are provided. The solution includes about 0.01 to about 1.0 parts by weight (pbw) of a polymer having phosphorylcholine groups, about 0.005 to about 0.05 pbw of a hydrophilic molecule, about 0.01 to about 1.0 pbw of an inorganic salt, and about 100 pbw of water. A number-average molecular weight of the polymer is about 4,000 to about 1,000,000 daltons. The polymer has a structure of formula (I):

wherein, in formula (I), m is a positive integer, n is zero or a positive integer, and R is C 2 -C 12 alkyl group, or C 2 -C 12 hydroxyalkyl group. When n is a positive integer, m/n is greater than 1. Moreover, a number-average molecular weight of the hydrophilic molecule is about 10,000 to about 5,000,000 daltons. The hydrophilic molecule is hyaluronic acid (HA) or hyaluronate salt.

Abstract translation: 提供了用于处理隐形眼镜和隐形眼镜包装系统的解决方案。 该溶液包含约0.01至约1.0重量份（pbw）具有磷酸胆碱基团的聚合物，约0.005至约0.05pbw的亲水分子，约0.01至约1.0pbw的无机盐和约100pbw的水。 聚合物的数均分子量为约4,000至约1,000,000道尔顿。 该聚合物具有式（I）的结构：其中，在式（I）中，m为正整数，n为零或正整数，并且R为C2-C12烷基或C2-C12羟烷基。 当n是正整数时，m / n大于1.此外，亲水分子的数均分子量为约10,000至约5,000,000道尔顿。 亲水分子是透明质酸（HA）或透明质酸盐。

公开(公告)号：EP3263684B1

公开(公告)日：2019-03-13

申请号：EP17157314.0

申请日：2017-02-22

Applicant: Pegavision Corporation

Inventor： LAI, Yu-Chin ,  YEH, Min-Tzong ,  CHANG, Han-Yi ,  CHANG, Ya-Hui

IPC: C11D3/00 ,  A61K9/00 ,  A61L12/00 ,  C11D3/22 ,  C11D3/37

公开(公告)号：EP3263683A1

公开(公告)日：2018-01-03

申请号：EP16195567.9

申请日：2016-10-25

Applicant: Pegavision Corporation

Inventor： CHANG, Han-Yi ,  LIAO, Ya-Hsuan ,  LU, Shu-Chen ,  CHANG, Ya-Hui ,  LAI, Yu-Chin

IPC: C11D3/00 ,  C11D3/04 ,  C11D3/37 ,  C11D7/10 ,  A61K9/00 ,  A61K9/08 ,  A61K47/32

CPC classification number: A61L12/14 ,  A61K9/0048 ,  A61K9/08 ,  A61K47/32 ,  C08F130/02 ,  C11D3/0078 ,  C11D3/042 ,  C11D3/046 ,  C11D3/168 ,  C11D3/365 ,  C11D3/3784 ,  C11D7/10

Abstract: A solution for treating contact lens is provided. The solution includes about 0.01-1.0 parts by weight (pbw) of a polymer having phosphorylcholine groups, about 0.01-1 pbw of an inorganic salt, and about 100 pbw of water. The polymer has a number-average molecular weight of about 4,000 to about 1,000,000 daltons and has a structure of formula (I):

wherein, in formula (I), m is a positive integer, n is zero or a positive integer, and R is C 2 -C 12 alkyl group or C 2 -C 12 hydroxyalkyl group. When n is a positive integer, m/n is greater than 1.

Abstract translation: 提供了用于处理隐形眼镜的解决方案。 该溶液包含约0.01-1.0重量份（pbw）的具有磷酸胆碱基团的聚合物，约0.01-1重量份的无机盐和约100重量份的水。 该聚合物具有约4,000至约1,000,000道尔顿的数均分子量，并具有式（I）的结构：其中，在式（I）中，m是正整数，n是零或正整数，并且R 是C 2 -C 12烷基或C 2 -C 12羟烷基。 当n是正整数时，m / n大于1。