公开(公告)号：EP1825267A2

公开(公告)日：2007-08-29

申请号：EP05852410.9

申请日：2005-11-29

申请人： Perkinelmer Life and Analytical Sciences

发明人： PATTON, Wayne, F. ,  SCHERMER, Mack, J. ,  BOBROW, Mark, N.

IPC分类号： G01N33/543

CPC分类号： G01N33/585 ,  G01N33/6842 ,  G01N2400/00 ,  G01N2400/10 ,  G01N2400/40 ,  G01N2400/50 ,  G01N2405/10

摘要： The present invention provides systems, methods and kits for performing multiplexed assays for glycoproteins using encoded particles as supports for glycoprotein specific binding agents.

摘要翻译： 本发明提供了用于使用编码的颗粒作为糖蛋白特异性结合剂的载体来进行糖蛋白的多重测定的系统，方法和试剂盒。

公开(公告)号：EP1943351A2

公开(公告)日：2008-07-16

申请号：EP06827672.4

申请日：2006-11-10

申请人： Perkinelmer Life and Analytical Sciences

发明人： PATTON, Wayne, F. ,  PANCHAGNULA, Venkateswarlu ,  MIKULSKIS, Alvydas

IPC分类号： C12Q1/00

CPC分类号： G01N33/6842 ,  C07K1/26 ,  G01N30/02 ,  G01N30/90 ,  G01N2030/388

摘要： A method for separating a sample comprising a plurality of compounds includes loading a sample onto a planar stationary phase, said sample comprising a plurality of compounds to be separated; and, while retaining the sample on the planar stationary phase, subjecting the sample to planar electrochromatographic separation in a selected direction using a first mobile phase; and subjecting the sample to a chromatographically-based separation in a direction other than that of the direction used for planar electrochromatographic separation using a second mobile phase. Separation is optionally followed by direct detection of analytes using mass spectrometry (MS). These three dimensions of separation are orthogonal to one another, providing for improved resolution of the analytes.