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">1.发明授权"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS 有权“（2-羟基-2-（4-羟基-3- HYDOXYMETHYLPHENYL）乙基氨基） - 丙基衍生物激动剂BETA2
公开(公告)号：EP1624868B9
公开(公告)日：2009-08-12
申请号：EP04730338.3
申请日：2004-04-29
申请人： Pfizer Limited , Pfizer Inc.
发明人： BUNNAGE, Mark Edward , GLOSSOP, Paul, Alan , LANE, Charlotte Alice Louise , LEWTHWAITE, Russell Andrew
IPC分类号： A61K31/4402 , C07C237/20 , C07D213/40 , C07C311/16 , A61K31/164 , C07D217/02 , C07D209/44 , A61K31/4035 , A61K31/472
CPC分类号： C07C237/20 , C07C237/22 , C07C311/46 , C07C2602/08 , C07D209/44 , C07D213/40 , C07D217/06
摘要： The invention relates to compounds of formula (1), and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
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">2.发明授权"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS 有权“（2-羟基-2-（4-羟基-3- HYDOXYMETHYLPHENYL）乙基氨基） - 丙基衍生物激动剂BETA2
公开(公告)号：EP1624868B1
公开(公告)日：2008-11-12
申请号：EP04730338.3
申请日：2004-04-29
申请人： Pfizer Limited , Pfizer Inc.
发明人： BUNNAGE, Mark Edward , GLOSSOP, Paul, Alan , LANE, Charlotte Alice Louise , LEWTHWAITE, Russell Andrew
IPC分类号： A61K31/4402 , C07C237/20 , C07D213/40 , C07C311/16 , A61K31/164 , C07D217/02 , C07D209/44 , A61K31/4035 , A61K31/472
CPC分类号： C07C237/20 , C07C237/22 , C07C311/46 , C07C2602/08 , C07D209/44 , C07D213/40 , C07D217/06
摘要： The invention relates to compounds of formula (1), and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
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公开(公告)号：EP1730103B1
公开(公告)日：2010-05-26
申请号：EP05708714.0
申请日：2005-03-10
申请人： Pfizer Limited , Pfizer Inc.
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
IPC分类号： C07C233/43 , C07C217/60 , A61K31/135
CPC分类号： C07C237/20 , C07C237/30 , C07C237/32 , C07C255/60 , C07C311/37 , C07C311/46 , C07C317/32 , C07C323/32 , C07C323/41 , C07C323/42 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D209/48 , C07D211/32 , C07D213/38 , C07D213/40 , C07D217/06 , C07D217/16 , C07D221/22 , C07D221/24 , C07D295/192 , C07D335/02
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译： 本发明涉及式（1）的化合物以及制备用于制备含这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病，病症和病症，特别是炎性，过敏和呼吸道疾病，病症和病症。
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公开(公告)号：EP1730103A1
公开(公告)日：2006-12-13
申请号：EP05708714.0
申请日：2005-03-10
申请人： Pfizer Limited , PFIZER INC.
发明人： BROWN, Alan, Daniel , BUNNAGE, Mark, Edward , GLOSSOP, Paul, Alan , JAMES, Kim , LANE, Charlotte, Alice, Louise , LEWTHWAITE, Russell, Andrew , PRICE, David, Anthony
IPC分类号： C07C233/43 , C07C217/60 , A61K31/135
CPC分类号： C07C237/20 , C07C237/30 , C07C237/32 , C07C255/60 , C07C311/37 , C07C311/46 , C07C317/32 , C07C323/32 , C07C323/41 , C07C323/42 , C07C2601/14 , C07C2602/08 , C07C2603/74 , C07D209/48 , C07D211/32 , C07D213/38 , C07D213/40 , C07D217/06 , C07D217/16 , C07D221/22 , C07D221/24 , C07D295/192 , C07D335/02
摘要： The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
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">5.发明公开"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL!PHENYL DERIVATIVES AS BETA2 AGONISTS 有权“（2-羟基-2-（4-羟基-3-羟基甲基苯基） - 乙酰胺） - 丙基苯酚衍生物
公开(公告)号：EP1624868A1
公开(公告)日：2006-02-15
申请号：EP04730338.3
申请日：2004-04-29
申请人： Pfizer Limited , PFIZER INC.
发明人： BUNNAGE, Mark Edward , GLOSSOP, Paul, Alan , LANE, Charlotte Alice Louise , LEWTHWAITE, Russell Andrew
IPC分类号： A61K31/4402 , C07C237/20 , C07D213/40 , C07C311/16 , A61K31/164 , C07D217/02 , C07D209/44 , A61K31/4035 , A61K31/472
CPC分类号： C07C237/20 , C07C237/22 , C07C311/46 , C07C2602/08 , C07D209/44 , C07D213/40 , C07D217/06
摘要： The invention relates to compounds of formula (1), and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
摘要翻译： 本发明涉及式（1）的化合物＆lt; CHEM＆gt;以及制备用于制备含有这些衍生物的组合物和用途的中间体的方法。 根据本发明的化合物可用于许多疾病，病症和病症，特别是炎性，过敏和呼吸道疾病，病症和病症。
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6.发明公开HYDROCHLORIDE SALT OF 5-[3-(3-HYDROXYPHENOXY)AZETIDIN-1-YL]-5-METHYL-2,2- DIPHENYLHEXANAMIDE 有权5-盐酸盐[3-（3-羟基苯氧基）氮杂环丁烷-1-基] -5-甲基-2,2- diphenylhexanamide
公开(公告)号：EP2125714A1
公开(公告)日：2009-12-02
申请号：EP08719316.5
申请日：2008-03-06
申请人： Pfizer Limited
发明人： GLOSSOP, Paul, Alan , JAMES, Kim
IPC分类号： C07D205/04 , A61K31/397 , A61P11/00
CPC分类号： C07D205/04
摘要： This invention relates to the hydrochloride salt of 5-[3-{3-hydroxyphenoxy)azetidin-1-yl]-5- methyl-2,2-diphenylhexanamide or derived form thereof and its use as a medicament.
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7.发明公开NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS 审中-公开NEUE，ALS MUSCARINREZEPTOR-ANTAGONISTEN AKTIVE VERBINDUNGEN
公开(公告)号：EP2200969A2
公开(公告)日：2010-06-30
申请号：EP08807004.0
申请日：2008-09-01
申请人： Pfizer Limited
IPC分类号： C07C217/60 , C07C235/34 , C07C311/29 , A61K31/137 , A61K31/166 , A61K31/18
CPC分类号： C07C235/48 , C07C217/60 , C07C233/21 , C07C233/60 , C07C235/34 , C07C311/29 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2603/74
摘要： The invention relates to compounds of formula: (I) processes and intermediates for their preparation, their use as muscarinic antagonists and pharmaceutical compositions containing them.
摘要翻译： 本发明涉及式的化合物及其制备中间体，它们用作毒蕈碱性拮抗剂和含有它们的药物组合物。
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公开(公告)号：EP2066626A1
公开(公告)日：2009-06-10
申请号：EP07804896.4
申请日：2007-09-04
申请人： Pfizer Limited
IPC分类号： C07D205/04 , A61K31/397
CPC分类号： C07D205/04
摘要： The invention relates to compounds of formula (I) processes and intermediates for their preparation, their use as muscarinic antagonists and pharmaceutical compositions containing them.
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9.发明授权HYDROCHLORIDE SALT OF 5-[3-(3-HYDROXYPHENOXY)AZETIDIN-1-YL]-5-METHYL-2,2- DIPHENYLHEXANAMIDE 有权盐酸5-羟基-5- [3-（3-羟基苯氧基）亚甲基-1-基] -5-甲基-2,2-二苯基甲酰胺
公开(公告)号：EP2125714B1
公开(公告)日：2011-06-08
申请号：EP08719316.5
申请日：2008-03-06
申请人： Pfizer Limited
发明人： GLOSSOP, Paul, Alan , JAMES, Kim
IPC分类号： C07D205/04 , A61K31/397 , A61P11/00
CPC分类号： C07D205/04
摘要： This invention relates to the hydrochloride salt of 5-[3-{3-hydroxyphenoxy)azetidin-1-yl]-5- methyl-2,2-diphenylhexanamide or derived form thereof and its use as a medicament.
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公开(公告)号：EP1928821B1
公开(公告)日：2009-01-07
申请号：EP06795581.5
申请日：2006-09-01
申请人： Pfizer Limited
发明人： GLOSSOP, Paul, Alan , MANTELL, Simon, John , STRANG, Ross, Sinclair , WATSON, Christine, Anne, Louise , WOOD, Anthony
IPC分类号： C07D207/12 , C07D413/12 , C07D211/46 , C07D205/04 , A61K31/397 , A61K31/40 , A61K31/4409 , A61P37/00
CPC分类号： C07D207/12 , C07D205/02 , C07D205/04 , C07D207/04 , C07D211/26 , C07D211/46 , C07D413/12
摘要： The invention relates to compounds of Formula (I) processes and intermediates for their preparation, their use as muscarinic antagonists and pharmaceutical composition containing them.
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