专利检索 ap:("Pfizer Products Inc.") AND inv:"Reaume, Andrew Gerard, Pfizer Global Reseach" 第 1 页

1.

发明公开
Creation of gene targeting vectors using homologous recombination in yeast 审中-公开
标题翻译：载体的构建通过在酵母中的同源重组的基因的靶向修饰

公开(公告)号：EP1184461A2

公开(公告)日：2002-03-06

申请号：EP01307021.4

申请日：2001-08-17

申请人： Pfizer Products Inc.

发明人： Fisher, Katherine Elizabeth, Pfizer Global Reseach , Reaume, Andrew Gerard, Pfizer Global Reseach

IPC分类号： C12N15/64 , C12N5/18 , A01K67/027 , C12N15/85

CPC分类号： C12N15/902 , A01K2217/075 , C12N2800/102 , C12N2840/203 , C12N2840/44

摘要： The present invention provides methods of preparing gene targeted mammalian cells having a targeted gene mutation, methods of making gene targeted mice, and gene targeting vectors that are useful in these methods.

摘要翻译： 本发明提供了制备具有目标基因突变的基因靶向的哺乳动物细胞的方法，使得基因靶向的小鼠，和基因靶向载体做的方法是在合成方法是有用的。