公开(公告)号：EP1843769A1

公开(公告)日：2007-10-17

申请号：EP05826405.2

申请日：2005-12-22

申请人： Pfizer Products Incorporated

发明人： JOHNSON, Barbara Alice ,  ZIEGLER, Carl, Bernard, Jr.

IPC分类号： A61K31/4985 ,  A61P1/00 ,  A61P1/04 ,  A61P3/04 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  A61P25/00 ,  A61P25/02 ,  A61P25/06 ,  A61P25/14 ,  A61P25/16 ,  A61P25/18 ,  A61P25/20 ,  A61P25/22

CPC分类号： A61K31/4985 ,  A61K9/0007 ,  A61K9/0056 ,  A61K9/2077 ,  A61K9/2081 ,  A61K9/2095 ,  A61K9/5047 ,  A61K9/7007

摘要： A fast disintegrating dosage form of varenicline comprising an effective amount of varenicline or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable excipient, wherein the dosage form disintegrates in a patient's oral cavity in less than three minutes. Also provided are a method for reducing nicotine addiction, aiding in the cessation of, or lessening of tobacco use in a subject by administering to the subject an effective amount of the fast disintegrating dosage form of varenicline or pharmaceutically acceptable salts thereof; a method of treating a disorder or condition by administering an effective amount of the fast disintegrating dosage form of varenicline; and, various methods of manufacturing or forming an immediate dosage form of varenicline.