公开(公告)号：EP1427706A1

公开(公告)日：2004-06-16

申请号：EP02763656.2

申请日：2002-09-19

申请人： Pharmacia Corporation

发明人： METZ, Suzanne ,  CLARE, Michael ,  CRICH, Joyce, Z. ,  HAGEN, Timothy, J. ,  HANSON, Gunnar, J. ,  HUANG, He ,  HOUDEK, Stephen, J. ,  STEALEY, Michael, A. ,  VAZQUEZ, Michael, L. ,  WEIER, Richard, M. ,  XU, Xiangdong

IPC分类号： C07D231/56 ,  C07D491/04 ,  C07D495/04 ,  C07D495/12 ,  C07D471/04 ,  A61K31/415 ,  A61K31/435

CPC分类号： C07D231/56 ,  C07D471/04 ,  C07D491/04 ,  C07D495/04 ,  C07D495/14

摘要： The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.

公开(公告)号：EP1444207A2

公开(公告)日：2004-08-11

申请号：EP02775879.6

申请日：2002-09-19

申请人： Pharmacia Corporation

发明人： BERGMANIS, Arija, A. ,  BONAFOUX, Dominique ,  CLARE, Michael ,  CRICH, Joyce, Z. ,  FLETCHER, Theresa, R. ,  GENG, Lifeng ,  HAGEN, Timothy, J. ,  HAMPER, Bruce, C. ,  HANSON, Gunnar, J. ,  HOUDEK, Stephen, C. ,  HUANG, He ,  IULA, Donna, M. ,  KOSZYK, Francis, J. ,  LENNON, Patrick, J. ,  LIAO, Shuyuan ,  LIAO, Subo ,  METZ, Suzanne ,  MOHLER, Scott, B. ,  NGUYEN, Maria ,  OBURN, David S. ,  OWEN, Thomas J. ,  PARTIS, Richard A. ,  SCATES, Angela M. ,  STEALEY, Michael A. ,  TOLLEFSON, Michael B. ,  VAZQUEZ, Michael L. ,  WEIER, Richard M. ,  WOLFSON, Serge G. ,  XU, Xiangdong

IPC分类号： C07D231/54 ,  A61K31/416 ,  A61P29/00 ,  C07D401/12 ,  C07D413/12 ,  C07D409/14 ,  C07D417/12 ,  C07D405/14 ,  C07D405/12 ,  C07D405/10 ,  C07D401/14

CPC分类号： C07D403/12 ,  C07D231/54 ,  C07D333/62 ,  C07D401/12 ,  C07D401/14 ,  C07D405/10 ,  C07D405/12 ,  C07D405/14 ,  C07D409/12 ,  C07D409/14 ,  C07D413/12 ,  C07D417/12

摘要： The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.

公开(公告)号：EP1427706B1

公开(公告)日：2007-05-30

申请号：EP02763656.2

申请日：2002-09-19

申请人： Pharmacia Corporation

发明人： METZ, Suzanne ,  CLARE, Michael ,  CRICH, Joyce, Z. ,  HAGEN, Timothy, J. ,  HANSON, Gunnar, J. ,  HUANG, He ,  HOUDEK, Stephen, J. ,  STEALEY, Michael, A. ,  VAZQUEZ, Michael, L. ,  WEIER, Richard, M. ,  XU, Xiangdong

IPC分类号： C07D231/56 ,  C07D491/04 ,  C07D495/04 ,  C07D495/12 ,  C07D471/04 ,  A61K31/415 ,  A61K31/435

CPC分类号： C07D231/56 ,  C07D471/04 ,  C07D491/04 ,  C07D495/04 ,  C07D495/14

摘要： The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.

公开(公告)号：EP1427707A1

公开(公告)日：2004-06-16

申请号：EP02763657.0

申请日：2002-09-19

申请人： Pharmacia Corporation

发明人： STEALEY, Michael, A. ,  CLARE, Michael ,  CRICH, Joyce, Z. ,  HANAU, Cathleen, E. ,  KOSZYK, Francis, J. ,  PARTIS, Richard, A. ,  XU, Xiangdong ,  WEIER, Richard, M.

IPC分类号： C07D231/56 ,  A61K31/415 ,  A61P19/02 ,  A61P35/00 ,  A61P29/00

CPC分类号： C07D231/56 ,  C07D401/04 ,  C07D405/04 ,  C07D471/04

摘要： The present invention relates to substituted indazole derivatives, compositions comprising such, intermediates, methods of making substituted indazolel derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.