公开(公告)号：EP1251126A3

公开(公告)日：2002-10-30

申请号：EP02008273.1

申请日：2002-04-19

申请人： Pharmacia Corporation, Corporate Patent Department

发明人： Brown, David L. ,  Graneto, Matthew J. ,  Ludwig, Cindy L. ,  Molyneaux, John M. ,  Talley, John J.

IPC分类号： C07D231/12 ,  C07D401/04 ,  C07D261/08 ,  C07D413/04

CPC分类号： C07D231/12 ,  C07D261/08 ,  C07D307/32

摘要： Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds corresponding to Formula I: wherein A, X, n, R 1 , R 2 , and R 3 are as described in the specification, and novel fluoro-substituted benzenesulfonyl compounds within Formula I.

公开(公告)号：EP1251126A2

公开(公告)日：2002-10-23

申请号：EP02008273.1

申请日：2002-04-19

申请人： Pharmacia Corporation, Corporate Patent Department

发明人： Brown, David L. ,  Graneto, Matthew J. ,  Ludwig, Cindy L. ,  Molyneaux, John M. ,  Talley, John J.

IPC分类号： C07D231/12 ,  C07D401/04 ,  C07D261/08 ,  C07D413/04

CPC分类号： C07D231/12 ,  C07D261/08 ,  C07D307/32

摘要： Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds corresponding to Formula I:
wherein A, X, n, R 1 , R 2 , and R 3 are as described in the specification, and novel fluoro-substituted benzenesulfonyl compounds within Formula I.

摘要翻译： 治疗环加氧酶-2介导的病症的方法包括向受试者施用治疗有效量的对应于式I的一种或多种氟取代的苯磺酰基化合物：其中A，X，n，R 1，R 2， 和R 3如说明书中所述，以及式I中的新的氟取代的苯磺酰基化合物。