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1.
公开(公告)号:EP2235022A1
公开(公告)日:2010-10-06
申请号:EP08864687.2
申请日:2008-12-22
申请人: Pierre Fabre Medicament , Centre National de la Recherche Scientifique - CNRS , UNIVERSITE PARIS-SUD 11
发明人: BEGUE, Jean-Pierre , BONNET-DELPON, Danièle , CROUSSE, Benoît , GRELLEPOIS, Fabienne , CHOLLET, Constance , FAHY, Jacques , MORDANT, Céline
IPC分类号: C07D493/18 , A61K31/35 , A61K31/357
CPC分类号: C07D519/00 , C07F9/6561
摘要: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I) : or a pharmaceutically acceptable salt thereof with B1 and B2 selected from C=O, CHOH and CH2, as well as to their use in treating cancer and to their preparation method.
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2.
公开(公告)号:EP2235022B1
公开(公告)日:2015-08-05
申请号:EP08864687.2
申请日:2008-12-22
申请人: Pierre Fabre Médicament , Centre National de la Recherche Scientifique (CNRS) , UNIVERSITE PARIS-SUD 11
发明人: BEGUE, Jean-Pierre , BONNET-DELPON, Danièle , CROUSSE, Benoît , GRELLEPOIS, Fabienne , CHOLLET, Constance , FAHY, Jacques , MORDANT, Céline
IPC分类号: C07D493/18 , A61K31/35 , A61K31/357
CPC分类号: C07D519/00 , C07F9/6561
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