公开(公告)号：EP1196210A1

公开(公告)日：2002-04-17

申请号：EP00937100.6

申请日：2000-06-09

申请人： PowderJect Research Limited

发明人： KENDALL, Mark A. F. ,  BROWN, Garry

IPC分类号： A61M5/30

CPC分类号： G11B20/00 ,  A61M5/2046 ,  A61M5/3015

摘要： The invention provides a device which seeks to ensure that substantially all the particles delivered avoid interaction with the so-called 'starting process'. There is provided a needleless injection device comprising a driver chamber (51) arranged, in use, to contain a charge of pressurised gas, a duct section (52) connected to the driver chamber (51) to receive gas therefrom and a closure means (53) for preventing the flow of gas from the driver chamber (51) to the duct section (52) until the closure means (53) is opened. Further, a dose of particles (58) is positioned within the device in the region of the closure means (53). The device is so constructed and arranged that upon opening of the closure means (53), a primary shock wave is produced to travel along the duct (52) in a downstream direction so that a substantially quasi-steady gas flow is established in the duct (52) upstream of the primary shock wave, with the dose of particles (58) being substantially wholly entrained in the substantially quasi-steady flow to be accelerated thereby and expelled from the device.

摘要翻译： 本发明提供了一种装置，其试图确保基本上所有传送的颗粒避免与所谓的“启动过程”相互作用。 提供了一种无针注射装置，包括在使用中布置成容纳一定量的加压气体的驱动器室（51），连接到驱动器室（51）以从其接收气体的管道部分（52）和封闭装置 用于防止气体从驱动室（51）流到管道部分（52）直到封闭装置（53）打开。 此外，一定剂量的颗粒（58）在封闭装置（53）的区域内定位在装置内。 该装置的构造和布置使得在打开封闭装置（53）时产生主要冲击波以沿着管道（52）在下游方向上行进，从而在管道中建立基本上准稳定的气流 （52），其中颗粒（58）的剂量基本上全部夹带在基本上准稳定的流动中，从而被加速并从装置排出。

公开(公告)号：EP1196210B1

公开(公告)日：2005-08-17

申请号：EP00937100.6

申请日：2000-06-09

申请人： PowderJect Research Limited

发明人： KENDALL, Mark A. F. ,  BROWN, Garry

IPC分类号： A61M5/30

CPC分类号： G11B20/00 ,  A61M5/2046 ,  A61M5/3015

摘要： The invention provides a device which seeks to ensure that substantially all the particles delivered avoid interaction with the so-called "starting process". There is provided a needleless injection device comprising a driver chamber (51) arranged, in use, to contain a charge of pressurised gas, a duct section (52) connected to the driver chamber (51) to receive gas therefrom and a closure means (53) for preventing the flow of gas from the driver chamber (51) to the duct section (52) until the closure means (53) is opened. Further, a dose of particles (58) is positioned within the device in the region of the closure means (53). The device is so constructed and arranged that upon opening of the closure means (53), a primary shock wave is produced to travel along the duct (52) in a downstream direction so that a substantially quasi-steady gas flow is established in the duct (52) upstream of the primary shock wave, with the dose of particles (58) being substantially wholly entrained in the substantially quasi-steady flow to be accelerated thereby and expelled from the device.