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公开(公告)号：EP2155675A1
公开(公告)日：2010-02-24
申请号：EP08768252.2
申请日：2008-06-09
申请人： Provid Pharmaceuticals, Inc. , The United States of America as represented by the Department of Health and Human Services
发明人： SHOEMAKER, Robert , CARDELLINA, John , CURRENS, Michael , KONDAPAKA, Sudhir , POMMIER, Yves , JOBSON, Andy , SCUDIERO, Dominic , WAUGH, David , LOUNTOS, George , COOK, Charles, M. , ZHANG, Guangtao , COLASANTI, Andrew , SELF, Christopher, R.
IPC分类号： C07D209/42 , C07D209/60 , C07D213/86 , C07D217/26 , C07D231/56 , C07D233/52 , C07D239/42 , C07D277/50 , C07D277/82 , C07D307/68 , C07D307/85 , C07D401/12 , C07D403/12 , C07D471/04 , A61K31/34
CPC分类号： C07D209/42 , C07D209/60 , C07D213/86 , C07D217/26 , C07D231/56 , C07D233/52 , C07D239/42 , C07D277/50 , C07D277/82 , C07D307/68 , C07D307/85 , C07D401/12 , C07D403/12 , C07D471/04
摘要： Provided herein are Compounds having the following structure: formula (I) wherein A, L, X and ring B are as defined herein, compositions comprising an effective amount of a Compound and methods for treating or preventing cancer, hypoxia, diabetes, stroke, autoimmune disease or a condition treatable or preventable by inhibition of Chk2, the ATM-Chk2 pathway or RSK2 comprising administering an effective amount of a Compound to a patient in need thereof.
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公开(公告)号：EP2155675B1
公开(公告)日：2014-02-19
申请号：EP08768252.2
申请日：2008-06-09
申请人： Provid Pharmaceuticals, Inc. , The United States of America as represented by the Department of Health and Human Services
发明人： SHOEMAKER, Robert , CARDELLINA, John , CURRENS, Michael , KONDAPAKA, Sudhir , POMMIER, Yves , JOBSON, Andy , SCUDIERO, Dominic , WAUGH, David , LOUNTOS, George , COOK, Charles, M. , ZHANG, Guangtao , COLASANTI, Andrew , SELF, Christopher, R.
IPC分类号： C07D209/42 , C07D209/60 , C07D213/86 , C07D217/26 , C07D231/56 , C07D233/52 , C07D239/42 , C07D277/50 , C07D277/82 , C07D307/68 , C07D307/85 , C07D401/12 , C07D403/12 , C07D471/04 , A61K31/34
CPC分类号： C07D209/42 , C07D209/60 , C07D213/86 , C07D217/26 , C07D231/56 , C07D233/52 , C07D239/42 , C07D277/50 , C07D277/82 , C07D307/68 , C07D307/85 , C07D401/12 , C07D403/12 , C07D471/04
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3.发明公开INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF 有权MHC II类分子抗原提呈的抑制剂，其使用方法
公开(公告)号：EP1605963A2
公开(公告)日：2005-12-21
申请号：EP04711176.0
申请日：2004-02-13
摘要： The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
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4.发明授权INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF 有权MHC II类分子抗原提呈的抑制剂，其使用方法
公开(公告)号：EP1605963B1
公开(公告)日：2011-11-16
申请号：EP04711176.0
申请日：2004-02-13
IPC分类号： A61K38/08 , A61K38/10 , A61K38/06 , C07K7/08 , C07K7/06 , C07K5/10 , C07K5/08 , A61P3/10 , A61P19/02 , A61P37/02 , A61P37/06
摘要： The present invention relates to compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds of the invention are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
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5.发明公开INHIBITORS OF ANTIGEN PRESENTATION BY MHC CLASS II MOLECULES AND METHODS OF USE THEREOF 审中-公开抗原呈递，MHC II类分子的供其使用抑制剂和方法
公开(公告)号：EP2229399A1
公开(公告)日：2010-09-22
申请号：EP08856845.6
申请日：2008-12-02
CPC分类号： C07K5/1016 , C07K7/02 , C07K7/06
摘要： Provided herein are novel compounds, pharmaceutical compositions containing such compounds and methods for their use. In particular, the compounds described herein are useful for the treatment or prevention of diseases associated with T cell proliferation such as autoimmune diseases and disorders.
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6.发明公开
公开(公告)号：EP4308585A1
公开(公告)日：2024-01-24
申请号：EP22771941.6
申请日：2022-03-09
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