专利检索 ap:("Puget Sound Blood Center") AND inv:"PRATT, Kathleen" 第 1 页

1.

发明公开
FACTOR VIII T CELL EPITOPE VARIANTS HAVING REDUCED IMMUNOGENICITY 审中-公开
标题翻译：具有降低的免疫原性因子VIII细胞表位的变体

公开(公告)号：EP2498803A2

公开(公告)日：2012-09-19

申请号：EP10830866.9

申请日：2010-11-15

申请人： Puget Sound Blood Center

发明人： PRATT, Kathleen , ETTINGER, Ruth , JAMES, Eddie. Arthur.

IPC分类号： A61K38/37

CPC分类号： C07K14/755 , A61K38/00

摘要： Provided herein are methods and compositions for preventing or reducing an initial immune response to factor VIII in patients suffering from hemophilia A, and for reducing the intensity of the immune response in patients having pre-formed inhibitor antibodies against factor VIII.

2.

发明公开
FACTOR VIII B CELL EPITOPE VARIANTS HAVING REDUCED IMMUNOGENICITY 审中-公开
标题翻译：因子VIII的B细胞表位的变体具有降低的免疫原性

公开(公告)号：EP2498804A2

公开(公告)日：2012-09-19

申请号：EP10830867.7

申请日：2010-11-15

申请人： Puget Sound Blood Center , James, Eddie Arthur

发明人： PRATT, Kathleen , ETTINGER, Ruth , JAMES, Eddie, Arthur

IPC分类号： A61K38/37

CPC分类号： C07K14/755 , A61K38/00

摘要： Provided herein are methods and compositions for preventing or reducing an initial immune response to factor VIII in patients suffering from hemophilia A, and for reducing the intensity of the immune response in patients having pre-formed inhibitor antibodies against factor VIII.