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公开(公告)号：EP4096676A1
公开(公告)日：2022-12-07
申请号：EP21748282.7
申请日：2021-01-29
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , LINDEMAN, Spencer, D. , MUKKAMALA, Ramesh
IPC: A61K31/704 , A61K47/54 , A61P35/00
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公开(公告)号：EP3838298A2
公开(公告)日：2021-06-23
申请号：EP20196752.8
申请日：2008-08-15
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , KULARATNE, Sumith, A.
IPC: A61K49/00 , A61K31/426 , A61K31/4745 , A61K31/475 , A61K47/54 , A61K51/04 , A61P13/08 , A61P25/28 , A61P35/00 , A61P43/00
Abstract: Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.
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公开(公告)号：EP2349274A1
公开(公告)日：2011-08-03
申请号：EP09815218.4
申请日：2009-09-17
Applicant: Endocyte, Inc. , Purdue Research Foundation
IPC: A61K31/517 , A61P11/06
CPC classification number: A61K47/48338 , A61K31/475 , A61K31/517 , A61K47/55 , A61K47/551 , C07D487/04
Abstract: Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.
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4.发明授权METHOD FOR BREASTCANCER PROGNOSIS USING CELLULAR FOLATE VITAMIN RECEPTOR QUANTIFICATION 有权预后乳腺癌的方法应用数量蜂窝叶酸维生素受体的
公开(公告)号：EP1864133B1
公开(公告)日：2010-03-10
申请号：EP06739883.4
申请日：2006-03-30
Applicant: Purdue Research Foundation , Endocyte, Inc. , MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventor： LOW, Philip, Stewart , HARTMANN, Lynn, C. , LEAMON, Christopher, Paul , ELLIS, Phil, Ronald
IPC: G01N33/569 , G01N33/53
CPC classification number: G01N33/57492
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公开(公告)号：EP4395782A1
公开(公告)日：2024-07-10
申请号：EP22865459.6
申请日：2022-08-30
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , NAPOLEON, John, Victor
IPC: A61K31/54 , A61K31/33 , A61K31/407 , A61K31/416 , A61K31/395 , A61K47/16
CPC classification number: A61K9/0019 , A61K47/55 , A61K47/555 , A61K47/545 , A61K47/551 , C12N2510/0020130101 , C12N5/0636 , C07K14/705 , C07K14/7051 , C07K2319/0320130101 , C07K2319/6020130101
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Patent Agency Ranking
公开(公告)号：EP3838298A3
公开(公告)日：2021-12-01
申请号：EP20196752.8
申请日：2008-08-15
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , KULARATNE, Sumith, A.
IPC: A61K49/00 , A61K31/426 , A61K31/4745 , A61K31/475 , A61K47/54 , A61K51/04 , A61P13/08 , A61P25/28 , A61P35/00 , A61P43/00
Abstract: Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.
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公开(公告)号：EP2187965B1
公开(公告)日：2019-10-09
申请号：EP08798020.7
申请日：2008-08-15
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , KULARATNE, Sumith, A.
IPC: A61K39/395 , C12P21/00 , A61K49/00 , A61K51/04 , A61P35/00
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公开(公告)号：EP0466816B1
公开(公告)日：1997-11-26
申请号：EP90906542.7
申请日：1990-04-02
Applicant: PURDUE RESEARCH FOUNDATION
Inventor： LOW, Philip, Stewart , HORN, Mark, Alan , HEINSTEIN, Peter, Frederick
IPC: C12N15/00
CPC classification number: B82Y5/00 , A61K47/551 , A61K47/557 , A61K47/665 , A61K49/001 , A61K51/0497 , C07B59/004 , C12N15/64 , C12N15/8206 , C12N15/87 , C12Q1/68
Abstract: A method is provided for enhancing transmembrane transport of exogenous molecules. The method comprises contacting a membrane of a living cell with a complex formed between said molecules and ligands selected from biotin, biotin analogs and other biotin receptor-binding ligands, and/or folic acid, folate analogs and other folate receptor-binding ligands to initiate receptor mediated transmembrane transport of the ligand complex. The method is used for the efficient delivery of peptides, proteins, nucleic acids and other compounds capable of modifying cell function into plant, animal, yeast, and bacterial cells.
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公开(公告)号：EP4464384A3
公开(公告)日：2025-01-08
申请号：EP24202375.2
申请日：2008-08-15
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , KULARATNE, Sumith, A
Abstract: Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.
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公开(公告)号：EP4096677A1
公开(公告)日：2022-12-07
申请号：EP21748466.6
申请日：2021-01-29
Applicant: Purdue Research Foundation
Inventor： LOW, Philip, Stewart , LINDEMAN, Spencer, D. , MUKKAMALA, Ramesh
IPC: A61K31/704 , A61K47/54 , A61P35/00
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