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1.发明公开PHOTOCHEMOTHERAPEUTIC METHOD USING 5-AMINOLEVULINIC ACID AND OTHER PRECURSORS OF ENDOGENOUS PORPHYRINS 失效USING A原卟啉IX PRECURSOR治疗皮肤真菌和疟疾此后SAID原卟啉光活化
公开(公告)号：EP0831909A1
公开(公告)日：1998-04-01
申请号：EP96915923.0
申请日：1996-06-03
发明人： KENNEDY, James, C. , POTTIER, Roy, H. , REID, Robert, L. , SAC-MORALES, Arnold , TOMALTY, Lewis, L.
CPC分类号： A61K49/0021 , A61K41/0061
摘要： Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluroescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.
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2.发明授权USE OF A PROTOPORPHYRIN IX PRECURSOR IN THE TREATMENT OF DERMATOPHYTOSES AND MALARIA AFTER PHOTOACTIVATION OF SAID PROTOPORPHYRIN 失效USING A原卟啉IX PRECURSOR治疗皮肤真菌和疟疾此后SAID原卟啉光活化
公开(公告)号：EP0831909B1
公开(公告)日：2005-01-26
申请号：EP96915923.5
申请日：1996-06-03
发明人： KENNEDY, James, C. , POTTIER, Roy, H. , REID, Robert, L. , SAC-MORALES, Arnold , TOMALTY, Lewis, L.
IPC分类号： A61K31/195 , A61K41/00 , A61K49/00 , A61P33/06 , A61P31/10
CPC分类号： A61K49/0021 , A61K41/0061
摘要： Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluroescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.
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