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    Method of preparing enhanced efficacy aluminum chlorhydrate antiperspirant and antiperspirant composition
    2.
    发明公开
    Method of preparing enhanced efficacy aluminum chlorhydrate antiperspirant and antiperspirant composition 失效
    一种用于止汗Aluminiumoxychlorids更高的功效和止汗剂组合物的制备方法。

    公开(公告)号：EP0183171A2

    公开(公告)日：1986-06-04

    申请号：EP85114693.6

    申请日：1985-11-19

    申请人： REHEIS, INC.

    发明人： Murray, Robert W. ,  Nelson, Roger E. ,  Rubino, Andrew M.

    IPC分类号： C01F7/56 ,  A61K7/38

    CPC分类号： A61Q15/00 ,  A61K8/26 ,  C01F7/56 ,  C01P2002/87

    摘要： Two-thirds to five-sixths basic aluminum chlorides having enhanced antiperspirant efficacy are produced by heating an aqueous solution containing about 40 to about 50 weight percent of the basic aluminum chloride to a temperature of at least about 130 degrees C for about one to twelve hours in a closed vessel, with the heating time being inversely proportionai to the temperature. Five-sixths basic aluminum chlorides treated in this manner are characterized by a size exclusion chromatogram having a single major peak with its apex at a relative retention time of about 0.75 - 0.79. The basic aluminum chlorides may be incorporated into any of the conventional antiperspirant forms with non-toxic, dermatologically acceptable carriers.

    摘要翻译： 三分之二到六分之五碱式铝氯化物具有增强的止汗效果通过加热重量的wässrige溶液含有的碱性氯化铝约40至约50％至至少约130摄氏度的温度下进行约1至12小时产生 在密闭容器中，与加热时间是反比于温度。 0.79 - 以这种方式处理的六分之五碱式铝氯化物通过在约0.75的相对保留时间具有其顶点单一主峰尺寸排阻色谱特征的。 基本铝氯化物可被结合到任何与非毒性的，皮肤病学上可接受的载体的常规止汗形式。

    Preparation of co-dried aluminium oxyhydroxides
    4.
    发明公开
    Preparation of co-dried aluminium oxyhydroxides 失效
    Herstellung von mischgetrockneten Aluminiumoxyhydroxyden。

    公开(公告)号：EP0072142A2

    公开(公告)日：1983-02-16

    申请号：EP82303962.3

    申请日：1982-07-27

    申请人： REHEIS, INC.

    发明人： Rubino, Andrew M. ,  Siciliano, Arthur

    IPC分类号： C01F7/00 ,  A61K7/00 ,  A61K9/06 ,  A61K33/08

    CPC分类号： A61K33/08 ,  A61K8/26 ,  A61Q19/00 ,  C01F7/02

    摘要： Adsorptive, protein-binding aluminium oxyhydroxide is prepared by mixing an aqueous suspension of carbonate-free, highly hydrated, aluminium oxyhydroxide with a water soluble additive that provides coordinating moieties with the aluminium compound and drying the resultant mixture. The protein-binding aluminium oxyhydroxides can be made re-suspendable by acidifying to a pH from 4 to 6.5, the acidification being effected either before or after drying.

    摘要翻译： 通过将无碳酸盐，高度水合的羟基氧化铝的水悬浮液与提供与铝化合物的配位部分并干燥所得混合物的水溶性添加剂混合来制备吸附性蛋白质结合氢氧化铝。 蛋白质结合的羟基氧化铝可以通过酸化至4至6.5的pH使其可再悬浮，酸化在干燥之前或之后进行。