公开(公告)号：EP1647594A4

公开(公告)日：2006-09-13

申请号：EP04770969

申请日：2004-07-28

申请人： RES INST INNOVATIVE TECH EARTH

发明人： MURAKAMI SHIKIKO ,  NAKATA KAORI ,  OKINO SHOHEI ,  IKENAGA YUKO ,  INUI MASAYUKI ,  YUKAWA HIDEAKI

IPC分类号： C12N15/09 ,  C12N1/21 ,  C12P7/46

CPC分类号： C12R1/15 ,  C12P7/46

摘要： It is intended to provide an aerobic coryneform bacterium transformant in which lactose dehydrogenase gene is disrupted by a genetic engineering technique and which has been recombined so as to allow the overexpression of pyruvate carboxylase. This aerobic coryneform bacterium transformant can produce a dicarboxylic acid at a high production speed from saccharides.

摘要翻译： 旨在提供一种需氧棒状杆菌转化体，其中乳糖脱氢酶基因通过遗传工程技术被破坏并且已经被重组从而允许丙酮酸羧化酶的过表达。 这种好氧棒杆菌转化体可以由糖类以高生产速度生产二羧酸。