专利检索 ap:("RESEARCH CORPORATION TECHNOLOGIES, INC.") AND inv:"PIERCE, WILLIAM, M., JR." 第 1 页

1.

发明公开
TOPICALLY ACTIVE OCULAR GEM-DIACYLTHIADIAZOLE SULFONAMIDE CARBONIC ANHYDRASE INHIBITORS 失效
标题翻译：主要活性化合物GEM-二氨基二亚胺磺酰亚胺碳氢化合物抑制剂

公开(公告)号：EP0521986A4

公开(公告)日：1993-04-07

申请号：EP91906958

申请日：1991-03-18

申请人： RESEARCH CORPORATION TECHNOLOGIES, INC.

发明人： PIERCE, WILLIAM, M., JR.

IPC分类号： A61K31/41 , A61K31/433 , A61P1/04 , A61P3/00 , A61P7/10 , A61P25/08 , A61P27/02 , A61P27/06 , A61P43/00 , C07D285/12 , C07D285/125 , C07D285/135

CPC分类号： C07D285/135

2.

发明公开
TOPICALLY ACTIVE OCULAR BENZOTHIAZOLE SULFONAMIDE CARBONIC ANHYDRASE INHIBITORS 失效
标题翻译：主要活性化合物苯并噻唑磺酰胺碳氢化合物抑制剂

公开(公告)号：EP0521101A4

公开(公告)日：1993-04-21

申请号：EP91907333

申请日：1991-03-18

申请人： RESEARCH CORPORATION TECHNOLOGIES, INC.

发明人： PIERCE, WILLIAM, M., JR.

IPC分类号： A61K9/08 , A61K9/107 , A61K31/425 , A61K31/428 , A61P3/02 , A61P27/02 , A61P43/00 , C07D277/80

CPC分类号： C07D277/80

摘要： This invention is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R6 is hydrogen or lower alkyl; each R1 is hydrogen, lower alkyl, halogen, nitro, trihaloalkyl, lower alkoxy, formyl, lower alkanoyl, loweralkylamino or diloweralkylamino; Y is (II) or (III); X is O, S or NR5; R2 is OR7 or NR7R8; each R3 and R4 are independently hydrogen or lower alkyl; R5, R7 and R8 are independently hydrogen or lower alkyl; n is 0-3 and m is 0-6. These compounds are useful for treating glaucoma or assessing corneal function in mammals.