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1.NUCLEIC ACID MOLECULES WITH NOVEL CHEMICAL COMPOSITIONS CAPABLE OF MODULATING GENE EXPRESSION 审中-公开
标题翻译: 与新的化学成分NUKEINSÄURE分子有能力的基因的表达来调节公开(公告)号:EP1071753A2
公开(公告)日:2001-01-31
申请号:EP99919896.3
申请日:1999-04-19
发明人: THOMPSON, James, D. , BEIGELMAN, Leonid , MCSWIGGEN, James, A. , KARPEISKY, Alexander , BELLON, Laurent , REYNOLDS, Mark , ZWICK, Michael , JARVIS, Thale , WOOLF, Tod , HAEBERLI, Peter , MATULIC-ADAMIC, Jasenka
IPC分类号: C12N9/00
CPC分类号: C12N15/113 , A61K38/00 , C12N15/1135 , C12N15/1138 , C12N2310/15 , C12N2310/31 , C12N2310/315 , C12N2310/317 , C12N2310/321 , C12N2310/332 , C12N2310/3341 , C12N2310/341 , C12N2310/345 , C12N2310/346 , C12N2310/3521 , C12N2310/3527
摘要: The invention features nucleic acid molecules with novel combinations of chemical modifications which are able to modulate gene expression.
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2.REGULATION OF THE EXPRESSION OF TRANSCRIPTIONAL REPRESSOR GENES USING NUCLEIC ACID MOLECULES 审中-公开
标题翻译: 表达TRANSKIPTIONAL阻遏基因的调节工具NUKLEINSÄUREMOLEKULEN公开(公告)号:EP1165758A2
公开(公告)日:2002-01-02
申请号:EP00922089.8
申请日:2000-04-11
CPC分类号: C12N15/113 , A61K38/00 , C12N15/1138 , C12N15/635 , C12N2310/121 , C12N2310/321 , C12N2310/322 , C12N2310/3521
摘要: Nucleic acid molecules which inhibit the expression of repressor genes are described. Also described are methods for preparing and using such nucleic acid molecules.
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公开(公告)号:EP1115859A2
公开(公告)日:2001-07-18
申请号:EP99969438.3
申请日:1999-09-20
CPC分类号: C12N15/113 , A61K38/00 , C12N15/1137 , C12N2310/315 , C12N2310/317 , C12N2310/321 , C12N2310/346 , C12N2310/53 , C12N2310/3521
摘要: The invention features novel hairpin hybridizer nucleic acid molecules which are able to modulate gene expression; useful in target validation, gene function identification and in human therapeutics.
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