专利检索 ap:("RIKEN" OR "OSAKA BIOSCIENCE INSTITUTE") AND inv:"URADE, Y. 503, Granshitio-Shimogamo-Shikisaikan," 第 1 页

1.

发明公开
THREE-DIMENSIONAL STRUCTURE OF LIPOCALIN-TYPE PROSTAGLANDIN D SYNTHASE AND UTILIZATION OF THE SAME 审中-公开
标题翻译： DREIDIMENSIONALE STRUKTUR DER LIPOCALINARTIGEN PROSTAGLANDIN-D-SYNTHASE UND DEREN VERWENDUNG

公开(公告)号：EP1574569A1

公开(公告)日：2005-09-14

申请号：EP03780880.5

申请日：2003-12-18

申请人： RIKEN , OSAKA BIOSCIENCE INSTITUTE

发明人： MIYANO, Masashi c/o RIKEN, Harima Institute , YAMAMOTO, Masaki c/o RIKEN, Harima Institute , KUMASAKA, Takashi c/o RIKEN, Harima Institute , AGO, Hideo c/o RIKEN, Harima Institute , URADE, Y. 503, Granshitio-Shimogamo-Shikisaikan, , IRIKURA, Daisuke , ARITAKE, Kosuke

IPC分类号： C12N9/90 , C12N9/99 , C12N15/09 , C12Q1/533 , C07D401/06 , G06F17/30 , G06F17/50 , G01N33/50

CPC分类号： C12N9/0004 , C07K2299/00 , C12Q1/533

摘要： Crystals of lipocalin-type prostaglandin D synthase are produced and analyzed by X-ray difratometry to give the three dimensional structure of enzyme based on which an inhibitor of the enzyme can be designed and selected.

摘要翻译： 通过X射线分光光度法测定脂笼蛋白型前列腺素D合成酶的晶体，得到酶的三维结构，根据该结构可以设计和选择酶的抑制剂。