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公开(公告)号：EP0821068A3
公开(公告)日：1999-06-02
申请号：EP97301610.8
申请日：1997-03-11
申请人： ROHM AND HAAS COMPANY , THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE
IPC分类号： C12P13/02 , C07F9/09 , C07F9/113 , C07C237/02 , C07C215/10 , A61K31/16 , A61K31/13 , A61K31/66 , A01N37/46 , A01N59/26 , A01N33/08
CPC分类号： A61K31/661 , A01N33/08 , A01N37/20 , A01N49/00 , A01N57/12 , A61K45/00 , C07F9/091 , C07F9/113 , C12P13/02
摘要： A process for novel sphingolipids and other secondary sphingosine-based compounds is provided which comprises the culturing of an appropriate fungus, harvesting mycelium from the fungus and isolating the sphingolipid from the mycelium. The sphingosine-based materials inhibit protein kinase C, provide an anti-inflammatory effect or provide an anti-tumor effect; furthermore, these sphingosine-based materials provide protection for plants against pathogenic microorganisms.
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公开(公告)号：EP0821068A2
公开(公告)日：1998-01-28
申请号：EP97301610.8
申请日：1997-03-11
申请人： ROHM AND HAAS COMPANY , THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE
IPC分类号： C12P13/02 , C07F9/09 , C07F9/113 , C07C237/02 , C07C215/10 , A61K31/16 , A61K31/13 , A61K31/66 , A01N37/46 , A01N59/26 , A01N33/08
CPC分类号： A61K31/661 , A01N33/08 , A01N37/20 , A01N49/00 , A01N57/12 , A61K45/00 , C07F9/091 , C07F9/113 , C12P13/02
摘要： A process for novel sphingolipids and other secondary sphingosine-based compounds is provided which comprises the culturing of an appropriate fungus, harvesting mycelium from the fungus and isolating the sphingolipid from the mycelium. The sphingosine-based materials inhibit protein kinase C, provide an anti-inflammatory effect or provide an anti-tumor effect; furthermore, these sphingosine-based materials provide protection for plants against pathogenic microorganisms.
摘要翻译： 提供新型鞘脂和其他次级鞘氨醇类化合物的方法，其包括培养合适的真菌，从真菌中收获菌丝体并从菌丝体中分离鞘脂。 基于鞘氨醇的物质抑制蛋白激酶C，提供抗炎作用或提供抗肿瘤作用; 此外，这些基于鞘氨醇的材料为防止病原微生物的植物提供保护。
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