公开(公告)号：EP3845563A3

公开(公告)日：2021-11-24

申请号：EP20207210.4

申请日：2007-10-02

申请人： Regeneron Pharmaceuticals, Inc.

发明人： STEVENS, Sean ,  HUANG, Tammy T ,  MARTIN, Joel H ,  FAIRHURST, Jeanette L ,  RAFIQUE, Ashique ,  TORRES, Marcela ,  POBURSKY, Kevin J ,  LEIDICH, Raymond W ,  WINDSOR, Joan A ,  MIKULKA, Warren R ,  AHRENS, Diana M ,  SHI, Ergang ,  PAPADOPOULOS, Nicholas J

IPC分类号： C07K16/28 ,  C12N15/13 ,  C12N5/12 ,  A61K39/395 ,  A61P37/00

摘要： An isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4Rα) with an affinity constant (K D ) of less than 200 pM, as measured by surface plasmon resonance.

公开(公告)号：EP3845563A2

公开(公告)日：2021-07-07

申请号：EP20207210.4

申请日：2007-10-02

申请人： Regeneron Pharmaceuticals, Inc.

发明人： STEVENS, Sean ,  HUANG, Tammy T ,  MARTIN, Joel H ,  FAIRHURST, Jeanette L ,  RAFIQUE, Ashique ,  TORRES, Marcela ,  POBURSKY, Kevin J ,  LEIDICH, Raymond W ,  WINDSOR, Joan A ,  MIKULKA, Warren R ,  AHRENS, Diana M ,  SHI, Ergang ,  PAPADOPOULOS, Nicholas J

IPC分类号： C07K16/28 ,  C12N15/13 ,  C12N5/12 ,  A61K39/395 ,  A61P37/00

摘要： An isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4Rα) with an affinity constant (K D ) of less than 200 pM, as measured by surface plasmon resonance.