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公开(公告)号：EP4143196A1
公开(公告)日：2023-03-08
申请号：EP21795690.3
申请日：2021-04-29
发明人： BOEZIO, Alessandro , DIPIETRO, Lucian V. , FRIDRICH, Cary Griffin , GUNAYDIN, Hakan , KURUKULASURIYA, Ravi , LESCARBEAU, Andre , MADER, Mary M. , MCLEAN, Thomas H. , PIERCE, Levi Charles Thomas , RAYNOR, Kevin David , SHORTSLEEVES, Kelley C. , TANG, Yong , TAYLOR, Alexander M. , WALTERS, W. Patrick , ZHANG, Hanmo , GIORDANETTO, Fabrizio , PECHERSKY, Yakov , WANG, Qi , ATIENZA, Bren-Jordan , BERTRAND-LAPERLE, Megan , BURNIE, Andrew J. , CHEN, Fei , CHITALE, Sampada , GELOZIA, Shorena , GIGUERE, Jean-Benoit , LANDAGARAY, Elodie , LARIVEE, Alexandre , LEPITRE, Thomas , MAERTENS, Gaetan , OUTIN, Johanne , PAL, Mohan , STURINO, Claudio , TANVEER, Kashif , THORAT, Rakesh , VEMULA, Naresh , KRUEGER, Elaine B. , PAN, Yue , DENINNO, Michael Paul , BOUSQUET, Yves , JOBIN-DES LAURIERS, Antoine , LEE, Jessica , MOHAMED, Tarek
IPC分类号： C07D487/04
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公开(公告)号：EP4370124A1
公开(公告)日：2024-05-22
申请号：EP22843033.6
申请日：2022-07-13
发明人： BOEZIO, Alessandro , TAYLOR, Alexander M. , FRIDRICH, Cary Griffin , GUNAYDIN, Hakan , DIPIETRO, Lucian V. , PIERCE, Levi Charles Thomas , MADER, Mary M. , KURUKULASURIYA, Ravi , MCLEAN, Thomas H. , PAN, Yue , DENINNO, Michael Paul , LARIVEE, Alexandre , BURNIE, Andrew J. , MEDENA, Caleb , MAERTENS, Gaetan , TANVEER, Kashif , PAL, Mohan , MOHAMED, Tarek , LEPITRE, Thomas , ATIENZA, Bren-Jordan , VEMULA, Naresh , GELOZIA, Shorena
IPC分类号： A61K31/4985 , A61P35/00 , C07D487/04
CPC分类号： C07D487/04 , A61P35/00 , C07D487/20 , C07D471/04 , C07D519/00
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公开(公告)号：EP4306529A3
公开(公告)日：2024-04-10
申请号：EP23210430.7
申请日：2020-05-12
发明人： TOURÉ, Bakary-Barry , SCHOENHERR, Heike , TAYLOR, Alexander M. , GIORDANETTO, Fabrizio , MOUSTAKAS, Demetri T. , MCLEAN, Thomas H. , HUDSON, Brandi M. , MADER, Mary M. , AYAZ, Pelin , SHARON, Dina A. , KURUKULASURIYA, Ravi , BOEZIO, Alessandro
IPC分类号： C07D519/00 , C07D471/14 , C07D487/04 , C07D491/04 , C07D498/04 , C07D498/22 , A61P35/00 , C07D471/04
摘要： The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of FGFR enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with FGFR signaling with the compounds and compositions of the disclosure.
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公开(公告)号：EP4399196A1
公开(公告)日：2024-07-17
申请号：EP22868344.7
申请日：2022-09-09
发明人： BOEZIO, Alessandro , TAYLOR, Alexander M. , GUNAYDIN, Hakan , ZHANG, Hanmo , RAYNOR, Kevin David , SHORTSLEEVES, Kelley C. , DIPIETRO, Lucian V. , PIERCE, Levi Charles Thomas , PABON, Nicolas , MCLEAN, Thomas H. , GIORDANETTO, Fabrizio , PECHERSKY, Yakov , WANG, Qi , LARIVEE, Alexandre , CHEN, Fei , MAERTENS, Gaetan , OUTIN, Johanne , BERTRAND-LAPERLE, Megan , PAL, Mohan , CHITALE, Sampada , DENINNO, Michael Paul
CPC分类号： A61P35/00
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公开(公告)号：EP4306529A2
公开(公告)日：2024-01-17
申请号：EP23210430.7
申请日：2020-05-12
发明人： TOURÉ, Bakary-Barry , SCHOENHERR, Heike , TAYLOR, Alexander M. , GIORDANETTO, Fabrizio , MOUSTAKAS, Demetri T. , MCLEAN, Thomas H. , HUDSON, Brandi M. , MADER, Mary M. , AYAZ, Pelin , SHARON, Dina A. , KURUKULASURIYA, Ravi , BOEZIO, Alessandro
IPC分类号： C07D519/00
摘要： The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of FGFR enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with FGFR signaling with the compounds and compositions of the disclosure.
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公开(公告)号：EP4387964A1
公开(公告)日：2024-06-26
申请号：EP22769821.4
申请日：2022-08-19
发明人： DIPIETRO, Lucian V. , KURUKULASURIYA, Ravi , MADEC, Amael , EVANS, Catherine A. , FRIDRICH, Cary Griffin , SWETT, Rebecca Jane , BOEZIO, Alessandro , TAYLOR, Alexander M. , MCLEAN, Thomas H. , THOMSON, Christopher
IPC分类号： C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D311/76 , C07D405/14 , A61K31/501 , A61P35/00
CPC分类号： C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D403/14 , C07D417/14 , C07D413/14 , C07D311/76 , C07D405/14 , A61P35/00
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公开(公告)号：EP4291176A1
公开(公告)日：2023-12-20
申请号：EP22753406.2
申请日：2022-02-11
发明人： TAYLOR, Alexander M. , BRIGGS, Timothy F. , PABON, Nicolas A. , HE, Jing , LESCARBEAU, Andre , BOEZIO, Alessandro , EVANS, Catherine A. , FRIDRICH, Cary Griffin , KELLEY, Brian P. , KRUEGER, Elaine B. , KURUKULASURIYA, Ravi , MCLEAN, Thomas H.
IPC分类号： A61K31/395 , A61K31/40 , C07D207/30
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公开(公告)号：EP3968999A1
公开(公告)日：2022-03-23
申请号：EP20805444.5
申请日：2020-05-12
发明人： TOURÉ, Bakary-Barry , SCHOENHERR, Heike , TAYLOR, Alexander M. , GIORDANETTO, Fabrizio , MOUSTAKAS, Demetri T. , MCLEAN, Thomas H. , HUDSON, Brandi M. , MADER, Mary M. , AYAZ, Pelin , SHARON, Dina A. , KURUKULASURIYA, Ravi , BOEZIO, Alessandro
IPC分类号： A61K31/519 , C07D487/04
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公开(公告)号：EP4412606A1
公开(公告)日：2024-08-14
申请号：EP22879536.5
申请日：2022-10-07
发明人： BOEZIO, Alessandro , TAYLOR, Alexander M. , ZHANG, Junyi , SHORTSLEEVES, Kelley C. , PIERCE, Levi Charles Thomas , MCLEAN, Thomas H. , KAPLAN, Anna , MADEC, Amaël , HUDSON, Brandi M. , MA, Jun , PAN, Yue , MAERTENS, Gaetan , OUTIN, Johanne
IPC分类号： A61K31/33 , A61K31/435 , A61K31/4545 , A61K31/505
CPC分类号： C07D471/04 , C07D311/22 , C07D405/12 , C07D405/04 , C07D405/14 , C07D239/95 , C07D405/06 , C07D417/12 , C07D487/04 , C07D519/00 , C07D401/14 , C07D401/12 , C07D401/04 , C07D491/056 , C07D403/04 , C07D239/88 , C07D239/91
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