专利检索 ap:("Rigel Pharmaceuticals, Inc.") AND inv:"KOLLURI, Rao, S., S." 第 1 页

1.

发明公开
HETEROCYCLIC ANTI-VIRAL COMPOUNDS COMPRISING METABOLIZABLE MOIETIES AND THEIR USES 审中-公开
标题翻译：杂环抗病毒化合物代谢组及其用途

公开(公告)号：EP1740556A1

公开(公告)日：2007-01-10

申请号：EP05726121.6

申请日：2005-03-25

申请人： Rigel Pharmaceuticals, Inc.

发明人： SINGH, Rajinder , GOFF, Dane , KOLLURI, Rao, S., S. , DARWISH, Ihab, S. , PARTRIDGE, John , COOPER, Robin , LU, Henry, H. , PARK, Gary

IPC分类号： C07D261/08 , C07D413/04 , A61K31/4439 , A61P31/12

CPC分类号： C07D413/04 , C07D261/08 , C07D413/12 , C07D413/14 , C07F9/65583

摘要： The present invention relates to substituted prodrug and compositions thereof useful for treating or preventing Hepatitis C virus (HCV) infections. In particular, the present invention relates to prodrugs of substituted diphenyl-, diheteroaryl- and mixed phenyl heteroaryl substituted five-membered heterocycle compounds, compositions comprising the compounds and the use of such compounds and compositions to inhibit HCV replication and/or proliferation as a therapeutic approach towards the treatment and/or prevention of HCV infections in humans and animals.