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1.发明公开METHODS FOR TREATING BONE CANCER PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST 无效疼痛治疗方法骨癌BY行政NGF拮抗剂
公开(公告)号：EP1732949A2
公开(公告)日：2006-12-20
申请号：EP05777592.6
申请日：2005-04-07
IPC分类号： C07K16/22
CPC分类号： C07K16/22 , A61K39/3955 , A61K2039/505 , C07K2317/24 , C07K2317/76
摘要： The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
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2.发明授权METHODS FOR TREATING BONE CANCER PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST 无效疼痛治疗方法骨癌BY行政NGF拮抗剂
公开(公告)号：EP1732949B1
公开(公告)日：2010-01-27
申请号：EP05777592.6
申请日：2005-04-07
IPC分类号： C07K16/22
CPC分类号： C07K16/22 , A61K39/3955 , A61K2039/505 , C07K2317/24 , C07K2317/76
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公开(公告)号：EP2305711B1
公开(公告)日：2017-08-02
申请号：EP10184427.2
申请日：2006-04-11
IPC分类号： A61K39/395 , A61P19/02 , A61P29/02 , C07K16/22
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
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4.发明公开Methods for treating osteoarthitis pain by administering a nerve growth factor antagonist and compositions containing the same 有权疼痛骨关节炎的治疗方法BY NGF拮抗剂的施用和含组合物
公开(公告)号：EP2305711A2
公开(公告)日：2011-04-06
申请号：EP10184427.2
申请日：2006-04-11
IPC分类号： C07K16/22
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
摘要翻译： 本发明涉及抗-NGF抗体（：例如抗-NGF拮抗剂抗体），多核苷酸和编码相同。 本发明还涉及使用检验和/或多核苷酸可用于治疗和/或预防疼痛，包括手术后疼痛，类风湿性关节炎疼痛，骨关节炎和疼痛的抗体。
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5.发明授权METHOD FOR TREATING PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST AND AN NSAID AND COMPOSITION CONTAINING THE SAME 有权方法用于治疗疼痛由神经生长因子拮抗剂的施用和NSAID及构成含有它们的
公开(公告)号：EP1594441B1
公开(公告)日：2010-12-15
申请号：EP04712940.8
申请日：2004-02-19
IPC分类号： A61K31/192 , A61K39/395 , A61P29/00
CPC分类号： C07K16/22 , A61K31/192 , A61K39/3955 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/76 , A61K2300/00
摘要： The present invention features methods for treating or preventing pain comprising administering an amount of a nerve growth factor antagonist (such as an anti-NGF antibody) and an amount of an NSAID such that together they provide effective pain relief. The invention also features compositions comprising a nerve growth factor antagonist and an NSAID and kits containing the same.
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6.发明公开METHODS FOR TREATING OSTEOARTHITIS PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING THE SAME 有权方法骨性关节炎疼痛由行政神经生长因子拮抗剂和这些组合物的治疗
公开(公告)号：EP1871416A2
公开(公告)日：2008-01-02
申请号：EP06750079.3
申请日：2006-04-11
IPC分类号： A61K39/395 , A61P19/02 , A61P29/02 , C07K16/22
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
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公开(公告)号：EP1575517A2
公开(公告)日：2005-09-21
申请号：EP03800170.7
申请日：2003-12-24
IPC分类号： A61K6/00
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
摘要翻译： 本发明涉及抗NGF抗体（例如抗NGF拮抗剂抗体）和编码其的多核苷酸。 本发明还涉及在治疗和/或预防疼痛（包括手术后疼痛，类风湿性关节炎疼痛和骨关节炎疼痛）中使用此类抗体和/或多核苷酸。
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8.发明授权METHODS FOR TREATING OSTEOARTHITIS PAIN BY ADMINISTERING A NERVE GROWTH FACTOR ANTAGONIST AND COMPOSITIONS CONTAINING THE SAME 有权方法骨性关节炎疼痛由行政神经生长因子拮抗剂和这些组合物的治疗
公开(公告)号：EP1871416B1
公开(公告)日：2012-07-18
申请号：EP06750079.3
申请日：2006-04-11
IPC分类号： A61K39/395 , A61P19/02 , A61P29/02 , C07K16/22
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
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公开(公告)号：EP1575517B1
公开(公告)日：2012-04-11
申请号：EP03800170.7
申请日：2003-12-24
IPC分类号： C07K16/22 , A61K39/395 , A61P25/04 , C07K14/48
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
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公开(公告)号：EP1581759A2
公开(公告)日：2005-10-05
申请号：EP03814397.0
申请日：2003-12-23
发明人： SHELTON, David, L.
IPC分类号： F16K25/00
CPC分类号： C07K16/2863 , A61K2039/505 , C07K2317/75
摘要： This invention relates to the field of taxol-induced neuropathy. More specifically, the invention relates to methods of treating taxol-induced sensory nauropathy comprising administration of agonist anti-trkC antibody for the treatment, prevention, and/or amelioration of a symptom of taxol-induced sensory neuropathy.
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