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公开(公告)号：EP3356385B1
公开(公告)日：2020-11-11
申请号：EP16778680.5
申请日：2016-09-19
发明人： CARDINALE, Jens , SCHÄFER, Martin , KOPKA, Klaus , EDER, Matthias , BAUDER-WUEST, Ulrike , EISENHUT, Michael , BENESOVA, Martina , HABERKORN, Uwe , GIESEL, Frederik L.
IPC分类号： C07K7/02 , G01N33/68 , G01N33/574 , C07D213/61
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2.发明公开
公开(公告)号：EP3356385A1
公开(公告)日：2018-08-08
申请号：EP16778680.5
申请日：2016-09-19
发明人： CARDINALE, Jens , SCHÄFER, Martin , KOPKA, Klaus , EDER, Matthias , BAUDER-WUEST, Ulrike , EISENHUT, Michael , BENESOVA, Martina , HABERKORN, Uwe , GIESEL, Frederik L.
IPC分类号： C07K7/02 , A61K38/08 , A61P35/00 , G01N33/68 , A61K38/03 , C07D213/61 , A61K31/465
摘要： The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
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公开(公告)号：EP4095130A1
公开(公告)日：2022-11-30
申请号：EP22178736.9
申请日：2014-10-17
发明人： EDER, Matthias , KOPKA, Klaus , SCHÄFER, Martin , BAUDER-WÜST, Ulrike , HABERKORN, Uwe , BENESOVA, Martina , MIER, Walter , KLIEM, Hans-Christian , KRATOCHWIL, Clemens
IPC分类号： C07D295/145 , C07B59/00 , A61K51/04 , A61P35/00
摘要： The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment of various disease states of prostate cancer.
Thus, the present invention concerns compounds that are represented by the general Formulae (Ia) or (Ib).-
公开(公告)号：EP3923998A1
公开(公告)日：2021-12-22
申请号：EP20703791.2
申请日：2020-02-14
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公开(公告)号：EP3713606A1
公开(公告)日：2020-09-30
申请号：EP18800987.2
申请日：2018-11-20
发明人： EDER, Matthias , KOPKA, Klaus , SCHAEFER, Martin , BAUDER-WUEST, Ulrike , HABERKORN, Uwe , BARANSKI, Ann-Christin , CARDINALE, Jens , BENESOVA, Martina
IPC分类号： A61K49/00 , A61K51/04 , C07D257/02 , G01N33/574 , G01N33/58 , A61K49/10
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6.发明公开
公开(公告)号：EP3923997A1
公开(公告)日：2021-12-22
申请号：EP20703784.7
申请日：2020-02-14
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公开(公告)号：EP3710068A1
公开(公告)日：2020-09-23
申请号：EP18796970.4
申请日：2018-11-12
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8.发明公开LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA), THEIR USE AS IMAGING AGENTS AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF PROSTATE CANCER 审中-公开前列腺特异膜抗原，标志着抑制剂（PSMA），它们作为造影剂和医药品前列腺癌的治疗
公开(公告)号：EP3038996A1
公开(公告)日：2016-07-06
申请号：EP14799340.6
申请日：2014-10-17
发明人： EDER, Matthias , KOPKA, Klaus , SCHÄFER, Martin , BAUDER-WÜST, Ulrike , HABERKORN, Uwe , EISENHUT, Michael , BENESOVA, Martina , MIER, Walter
IPC分类号： C07B59/00 , C07D295/145
CPC分类号： A61K51/0482 , C07B59/002 , C07D257/02 , C07D295/145
摘要： The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers, imaging agents and for the treatment of various disease states of prostate cancer. Thus, the present invention concerns compounds that are represented by the general Formulae (Ia) or (Ib).
摘要翻译： 本发明基因集会涉及到放射性药物领域及其核医学作为示踪剂，造影剂的使用和前列腺癌的各种疾病状态的治疗。 因此，本发明涉及的化合物也由通式（Ia）或（Ib）表示。
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9.发明公开HYDROPHOBIC MODIFIED PEPTIDES AND THEIR USE FOR LIVER SPECIFIC TARGETING 有权HYDROPHOB MODIFIZIERTE PEPTIDE UND IHRE VERWENDUNGFÜRLEBERSPEZIFISCHES TARGETING
公开(公告)号：EP2673004A1
公开(公告)日：2013-12-18
申请号：EP12704263.8
申请日：2012-02-10
发明人： MIER, Walter , URBAN, Stephan , MEHRLE, Stefan , HABERKORN, Uwe
IPC分类号： A61K49/00 , A61K49/08 , A61K51/08 , C07K14/005 , A61K47/48
CPC分类号： C07K7/08 , A61K47/542 , A61K47/64 , A61K51/0402 , A61K51/088 , C07K14/00
摘要： The present invention relates to hydrophobic modified peptides for the specific delivery of compounds to the liver, preferably to hepatocytes, in vitro as well as in vivo. The present invention relates to pharmaceutical compositions comprising said hydrophobic modified peptide(s) and the compound(s) to be specifically delivered to the liver. The present invention furthermore relates to the use of the inventive hydrophobic modified peptides as well as to a method for the prevention and/or treatment of liver diseases or disorders.
摘要翻译： 本发明涉及用于在体外和体内将化合物特异性递送至肝脏，优选肝细胞的疏水性修饰肽。 本发明涉及包含所述疏水性修饰肽和要特异性递送至肝脏的化合物的药物组合物。 本发明还涉及本发明的疏水性修饰肽的用途以及预防和/或治疗肝脏疾病或病症的方法。
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公开(公告)号：EP2928502B1
公开(公告)日：2019-01-23
申请号：EP13802328.8
申请日：2013-12-04
发明人： STRIEKER, Matthias , MIER, Walter , HABERKORN, Uwe
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