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公开(公告)号：EP2648718B1
公开(公告)日：2019-05-08
申请号：EP11846156.5
申请日：2011-12-09
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2.发明公开INSULIN-MIMETIC LOCAL THERAPEUTIC ADJUNCTS FOR ENHANCING SPINAL FUSION 审中-公开胰岛素MIME TABLES局部治疗附件的改进脊柱融合
公开(公告)号：EP2911614A1
公开(公告)日：2015-09-02
申请号：EP13849022.2
申请日：2013-10-25
CPC分类号： A61K33/30 , A61F2/4455 , A61F2002/30677 , A61F2310/00179 , A61F2310/00293 , A61F2310/00359 , A61F2310/0097 , A61K33/04 , A61K33/24 , A61K35/32 , A61K47/46 , A61L27/306 , A61L27/54 , A61L2300/102 , A61L2430/38
摘要： Bone tissue materials comprising insulin-mimetic agents, such as suitable zinc, vanadium, tungsten, molybdenum, niobium, selenium, and manganese compounds, for facilitating spinal fusion of vertebrae in spinal fusion surgical procedures, and methods thereof. Additionally provided is a bone tissue kit for facilitating fusion of vertebrae in a spinal fusion surgical procedure including a composition formulated for facile application in a spinal fusion procedure comprising an insulin-mimetic agent and a pharmaceutically acceptable carrier. Yet further provided is an implantable device for enhancing spinal fusion including a prosthetic implant configured to stabilize and promote the fusion of two adjacent vertebrae, wherein the bone tissue contacting surfaces of the prosthetic implant are coated with a composition comprising an insulin-mimetic agent.
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公开(公告)号：EP2523672B1
公开(公告)日：2016-07-13
申请号：EP11733440.9
申请日：2011-01-14
发明人： LIN, Sheldon, Suton , PAGLIA, David, Naisby , O'CONNOR, John, Patrick , BREITBART, Eric , BENEVENIA, Joseph
IPC分类号： A61K31/661 , A61K33/24 , A61K31/555 , A61P19/08 , A61L27/54 , A61K9/00 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/29 , A61K38/30 , A61K45/06 , A61K35/32 , A61K33/06 , A61K33/26
CPC分类号： A61K31/555 , A61K9/0019 , A61K9/0024 , A61K31/661 , A61K33/24 , A61K38/00 , A61K45/06 , A61L27/54 , A61L2300/102 , A61L2300/45 , A61L2430/02 , A61K2300/00
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