公开(公告)号：EP1093516A2

公开(公告)日：2001-04-25

申请号：EP99931753.0

申请日：1999-07-06

申请人： SCHERING CORPORATION

发明人： BATES, Elizabeth, Esther, Mary ,  LEBECQUE, Serge, J., E. ,  MURPHY, Erin, E. ,  MATTSON, Jeanine, D. ,  GORMAN, Daniel, M. ,  HEDRICK, Joseph, A. ,  WANG, Luquan ,  ZLOTNIK, Albert ,  MURGOLO, Nicholas, J. ,  GREENE, Jonathan, R. ,  JOHNSTON, James, A. ,  BAZAN, Jose, Fernando ,  MAHONY, Daniel ,  LEES, Emma, M.

IPC分类号： C12N15/12 ,  C12N15/19 ,  C12N15/57 ,  C12N15/62 ,  C07K16/18 ,  C07K16/28 ,  C07K16/24 ,  C07K16/40 ,  C12Q1/68 ,  G01N33/566 ,  G01N33/68 ,  A61K38/17 ,  A61K38/19 ,  A61K38/48

CPC分类号： C12N9/6472 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4738 ,  C07K14/521 ,  C07K14/70578 ,  C07K2319/00

摘要： Purified genes from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding the polypeptides are provided. Methods of using said reagents and diagnostic kits are also provided. Characterization of genes and products relating to DC-PGT (Dendritic cell prostaglandin-like transporter), HDTEA84, HSLJD37R and RANKL (related to TNF receptor family), HCC5 chemokine, Dub 11 and Dub 12 (Deubiquitinating 11 and 12), MD-1 and MD-2 (proteins which exhibit properties of ligands for proteins exhibiting a leucine-rich protein motif (LRR)) and cyclin E2.