公开(公告)号：EP0970741A4

公开(公告)日：2006-03-29

申请号：EP98932539

申请日：1998-07-15

申请人： SHISEIDO CO LTD

发明人： SEKINE TOMOKO ,  MATSUZAKI FUMIAKI ,  YANAKI TOSHIO ,  YAMAGUCHI MICHIHIRO

IPC分类号： A61K8/06 ,  A61K9/113 ,  A61Q19/00 ,  B01F17/28 ,  B01F13/00 ,  A61K7/00

CPC分类号： A61Q19/00 ,  A61K8/066 ,  A61K9/113 ,  Y10S514/941 ,  Y10S514/943 ,  Y10S514/944 ,  Y10S514/975 ,  Y10S516/902

摘要： An O/W/O type multiphase emulsion comprising an oily outer phase and an O/W type emulsion dispersed in the outer phase, characterized in that the O/W type emulsion present as the inner phase comprises either a combination of an amphiphilic substance and a surfactant which is selected from among those forming a gel in the amphiphilic substance/surfactant/oil/water system at ordinary temperature or above or a combination of an amphiphilic substance and an N-(long-chain acyl) acidic amino acid monosalt which is selected from among those forming a gel in the amphiphilic substance/N-(long-chain acyl) acidic amino acid monosalt/oil/water system at ordinary temperature or above, an oil component and water, that the oily outer phase contains both a clay mineral modified with an organic substance and an emulsifying agent having an HLB value of 7 or below, and that the weight ratio of the O/W type emulsion to the oily outer phase lies between 2:3 and 19:1. The O/W/O type multiphase emulsion is excellent in long-term stability and usability.