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公开(公告)号:EP1509529B1
公开(公告)日:2009-08-12
申请号:EP03730481.3
申请日:2003-05-28
申请人: SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. , ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI
发明人: MARZI, Mauro Sigma-Tau Ind. Farmaceutiche Riunite , ALLOATTI, Domenico Sigma-Tau Ind. Farmac. Riunite , PISANO, Claudio Sigma-Tau Ind. Farmac. Riunite , TINTI, Maria Ornella Sigma-Tau Ind. Farmac. Riunit , VESCI, Loredana Sigma-Tau Ind. Farmac. Riunite SPA , ZUNINO, Franco Ist.N. per lo Studio e la Cura Tumo
IPC分类号: C07D491/22 , A61K31/4375 , A61P35/00 , A61P31/12 , A61P33/00
CPC分类号: C07D491/22
摘要: Formula (I) compounds are described: (I) where the groups are as defined in the description here below, the racemic mixtures, their individual enantiomers, their individual diastereoisomers, their mixtures, and their pharmaceutically acceptable salts. Said compounds are topoisomerase I inhibitors.