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公开(公告)号:EP1686119B1
公开(公告)日:2009-07-29
申请号:EP06075890.1
申请日:2001-02-13
发明人: Hickey, Deidre, Mary, B. c/o GlaxoSmithKline , Ife, Robert, John c/o GlaxoSmithKline , Leach, Colin, Andrew c/o GlaxoSmithKline , Pinto, Ivan, Leo c/o GlaxoSmithKline , Smith, Stephen, Allan c/o GlaxoSmithKline , Stanway, Steven, James c/o GlaxoSmithKline
IPC分类号: C07D239/56 , C07D401/12 , C07D239/70 , C07D239/26 , C07D213/06 , C07D213/54 , C07C15/14 , A61K31/505 , A61P3/06
CPC分类号: C07D239/56 , C07D239/60 , C07D239/70 , C07D239/95 , C07D401/12 , C07D403/12 , C07D495/04
摘要: Pyrimidinone compounds of formula (I) are inhibitors of the enzyme LpPLA2 and are useful in the treatment of atherosclerosis
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公开(公告)号:EP1686119A1
公开(公告)日:2006-08-02
申请号:EP06075890.1
申请日:2001-02-13
发明人: Hickey, Deidre, Mary, B. c/o GlaxoSmithKline , Ife, Robert, John c/o GlaxoSmithKline , Leach, Colin, Andrew c/o GlaxoSmithKline , Pinto, Ivan, Leo c/o GlaxoSmithKline , Smith, Stephen, Allan c/o GlaxoSmithKline , Stanway, Steven, James c/o GlaxoSmithKline
IPC分类号: C07D239/56 , C07D401/12 , C07D239/70 , C07D239/26 , C07D213/06 , C07D213/54 , C07C15/14 , A61K31/505 , A61P3/06
CPC分类号: C07D239/56 , C07D239/60 , C07D239/70 , C07D239/95 , C07D401/12 , C07D403/12 , C07D495/04
摘要: Pyrimidinone compounds of formula (I) are inhibitors of the enzyme LpPLA2 and are useful in the treatment of atherosclerosis
摘要翻译: 式(I)的嘧啶酮化合物是LpPLA2酶的抑制剂,可用于治疗动脉粥样硬化
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