专利检索 ap:("SOCIETE DE CONSEILS DE RECHERCHESET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)") AND inv:"ROLLAND, Alain" 第 1 页

1.

发明公开
NOUVEAUX ANALOGUES TETRACYCLIQUES DE CAMPTOTHECINES, LEURS PROCEDES DE PREPARATION, LEUR APPLICATION COMME MEDICAMENTS ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT 有权
标题翻译：四环CAMPOTHECINEANALOGUE，PROCESS FOR他们对使用药物和装有药剂

公开(公告)号：EP1042323A1

公开(公告)日：2000-10-11

申请号：EP98962480.4

申请日：1998-12-16

申请人： SOCIETE DE CONSEILS DE RECHERCHESET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)

发明人： BIGG, Dennis , LAVERGNE, Olivier , ROLLAND, Alain , LANCO, Christophe , ULIBARRI, Gérard

IPC分类号： C07D471/14 , A61K31/44 , C07D213/64

CPC分类号： C07D213/64 , C07D471/14

摘要： The invention concerns novel camptothecin tetracyclic analogues of formula (I), preparation methods, applications as medicines and pharmaceutical compositions containing them. Said analogues, among which figures in particular 3-hydroxy-3-(4-oxo-4,6-dihydroindolizino [1,2-b] quinoline-2-yl)pentanoic acid, have a powerful biological activity for inhibiting topoisomerase I and/or topoisomerase II.