公开(公告)号：EP2440533A4

公开(公告)日：2013-03-27

申请号：EP10785625

申请日：2010-06-14

申请人： SOCPRA SCIENCES ET GENIE SEC

发明人： MULHBACHER JEROME ,  LAFONTAINE DANIEL ,  MALOUIN FRANCOIS ,  ALLARD MARIANNE ,  MARSAULT ERIC

IPC分类号： C07D239/46 ,  A61K31/513 ,  A61K31/519 ,  A61L2/16 ,  A61P31/04 ,  C07D239/48 ,  C07D239/50 ,  C07D239/56 ,  C07D498/04 ,  C07D513/04 ,  G01N33/569

CPC分类号： A61K31/675 ,  A61K31/4412 ,  A61K31/505 ,  A61K31/513 ,  A61K31/519 ,  A61K31/535 ,  A61K31/5383 ,  A61K31/54 ,  A61K31/542 ,  C07D239/46 ,  C07D239/48 ,  C07D239/50 ,  C07D498/04 ,  C07D513/04 ,  Y10T436/141111 ,  Y10T436/143333

摘要： The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against microorganisms bearing a guanine riboswitch that controls the expression of the guaA gene, including organisms which are resistant to certain antibiotic families, and which are useful as antibacterial agents for treatment or prophylaxis of bacterial infections in animals or in humans, in particular but not limited to infections of the mammary gland, or their use as antiseptics, agents for sterilization or disinfection.