公开(公告)号：EP4210822A1

公开(公告)日：2023-07-19

申请号：EP21773612.3

申请日：2021-09-09

申请人： SORBONNE UNIVERSITE ,  Centre national de la recherche scientifique ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  Institut National de la Santé et de la Recherche Médicale (INSERM)

发明人： PICAUD, Serge ,  CADONI, Sara ,  SAHEL, José-Alain ,  TANTER, Mickaël ,  DEMENE, Charlie

IPC分类号： A61N7/00 ,  A61K35/761 ,  C12N15/86 ,  A01K67/027

公开(公告)号：EP3353694A1

公开(公告)日：2018-08-01

申请号：EP16775610.5

申请日：2016-09-23

申请人： Institut National de la Santé et de la Recherche Médicale (INSERM) ,  Centre National de la Recherche Scientifique ,  Sorbonne Université ,  Université Paris Diderot (Paris 7) ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris

发明人： DEFFIEUX, Thomas ,  TANTER, Mickaël ,  GENNISSON, Jean-Luc ,  LENKEI, Zsolt ,  PERNOT, Mathieu

IPC分类号： G06F19/00

CPC分类号： G09B23/286 ,  A61B8/00 ,  A61B8/06 ,  A61B8/0816 ,  A61B8/42 ,  A61B8/4209 ,  A61B8/483 ,  G06F19/00 ,  G06T7/0012 ,  G06T2207/10136 ,  G06T2207/30016 ,  G16H50/50

摘要： The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.

公开(公告)号：EP3307175A1

公开(公告)日：2018-04-18

申请号：EP16732496.1

申请日：2016-06-09

申请人： Institut National de la Santé et de la Recherche Médicale (INSERM) ,  Centre National de la Recherche Scientifique ,  Université Pierre et Marie Curie (Paris 6) ,  Université Paris Diderot - Paris 7 ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris

发明人： GENNISSON, Jean-Luc ,  TANTER, Mickaël ,  DEFFIEUX, Thomas ,  PERNOT, Mathieu

IPC分类号： A61B8/08 ,  A61B8/00 ,  A61B5/04 ,  A61B5/11 ,  A61B8/06

CPC分类号： A61B8/4416 ,  A61B5/04001 ,  A61B5/0478 ,  A61B5/11 ,  A61B5/1118 ,  A61B8/06 ,  A61B8/0808 ,  A61B8/4209 ,  A61B8/481 ,  A61B8/488 ,  A61B2503/40 ,  A61B2562/0209 ,  A61B2562/0219 ,  A61B2562/066 ,  A61B2562/166

摘要： The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.

公开(公告)号：EP3310263A1

公开(公告)日：2018-04-25

申请号：EP16733014.1

申请日：2016-06-16

申请人： Institut National de la Santé et de la Recherche Médicale (INSERM) ,  Université Pierre et Marie Curie (Paris 6) ,  Université Paris Diderot (Paris 7) ,  Centre National de la Recherche Scientifique ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris

发明人： DEFFIEUX, Thomas ,  GENNISSON, Jean-Luc ,  TANTER, Mickaël ,  COHEN, Ivan ,  PERNOT, Mathieu

IPC分类号： A61B8/08 ,  A61B8/00

CPC分类号： A61B8/4209 ,  A61B5/0077 ,  A61B5/0478 ,  A61B8/0808 ,  A61B8/0816 ,  A61B8/145 ,  A61B8/4411 ,  A61B8/4416 ,  A61B8/4461 ,  A61B8/4488 ,  A61B8/488 ,  A61B8/543 ,  A61B2503/40 ,  A61B2562/0219

摘要： The invention concerns a detecting apparatus (12) for imaging at least two areas of a brain of a subject (10), the detecting apparatus (12) comprising:—a holder comprising:—a frame (14) devoted to be cemented on the skull of the subject (10), the frame (14) delimitating an inner portion (18) which is transparent to ultrasound waves,—a removable imaging device comprising:—a platform (16) delimitating an inner space (28), the inner space (28) facing the inner portion (18),—a fixing element (30) adapted to temporary fix and lock the platform (16) to the holder,—an ultrasound probe (32), and—a moving stage (34) holding the ultrasound probe (32) and being adapted to move the ultrasound probe (32) within the inner space (28).

公开(公告)号：EP3355790A1

公开(公告)日：2018-08-08

申请号：EP16778728.2

申请日：2016-09-29

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  Sorbonne Université ,  Université Paris Diderot - Paris 7 ,  Centre National de la Recherche Scientifique ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  Université Paris Descartes ,  Assistance Publique - Hôpitaux de Paris

发明人： PROVOST, Jean ,  GAROFALAKIS, Anikitos ,  PERNOT, Mathieu ,  TANTER, Mickaël ,  TAVITIAN, Bertrand ,  VIEL, Thomas

IPC分类号： A61B6/00 ,  A61B6/03 ,  A61B8/00 ,  G01S7/52

CPC分类号： A61B6/5247 ,  A61B6/032 ,  A61B6/037 ,  A61B6/4258 ,  A61B6/4417 ,  A61B8/06 ,  A61B8/4416 ,  A61B8/488 ,  A61B8/5261 ,  A61N7/00

摘要： The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a γ-ray, and c) determining the at least one property of the object based on the first data and the second data.

公开(公告)号：EP3099240A1

公开(公告)日：2016-12-07

申请号：EP15701563.7

申请日：2015-01-12

申请人： Centre National de la Recherche Scientifique (C.N.R.S.) ,  INSERM - Institut National de la Santé et de la Recherche Médicale ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  Université Paris Diderot (Paris 7)

发明人： TANTER, Mickaël ,  PERNOT, Mathieu ,  FINK, Mathias ,  GENNISSON, Jean-Luc

IPC分类号： A61B8/00 ,  A61B8/08 ,  G01N29/07

CPC分类号： A61B8/485 ,  A61B8/085 ,  A61B8/0858 ,  A61B8/0883 ,  A61B8/4281 ,  A61B8/4483 ,  A61B8/5223

摘要： The invention relates to a method for characterising a weak anisotropic medium (C) including fibres and having an outer surface (1), by observing, in various propagation directions, the propagation of a shear wave diverging from a central area (10) in the weak anisotropic medium. A propagation parameter of the shear wave in each of the propagation directions is deduced therefrom; then a direction of the fibres of the weak anisotropic medium is determined, as are a rheological elasticity parameter in a direction perpendicular to the fibres and a rheological elasticity parameter in the direction of the fibres.

公开(公告)号：EP3363498A1

公开(公告)日：2018-08-22

申请号：EP17305179.8

申请日：2017-02-17

申请人： Cardiawave ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  INSERM (Institut National de la Santé et de la Recherche Médicale) ,  Centre National de la Recherche Scientifique (CNRS) ,  Université Paris Diderot - Paris 7

发明人： TANTER, Mickaël ,  PERNOT, Mathieu ,  ROBIN, Justine

IPC分类号： A61N7/00 ,  A61N7/02 ,  A61B17/22 ,  A61B8/08

摘要： A method and system for secure ultrasound treatment of living tissues using an ultrasound probe (2) comprising a reflective cavity (9) in acoustic communication with living tissues (L), a transducer (6) to emit an ultrasound wave in the reflective cavity (9) and a transducer (6) to acquire a backscattered signal in the reflective cavity (9).
The method comprises the steps of
a) emitting a first ultrasound wave in the reflective cavity (9) that generates a backscattered ultrasound wave in the reflective cavity (9),
b) acquiring a backscattered signal in the reflective cavity,
c) determining whether an insonification can be safely performed by computing a similarity value between the backscattered signal and a predefined reference signal, and
d) if an insonification can be safely performed, treating the living tissues with a second ultrasound wave emitted in the reflective cavity (9). The second ultrasound wave is focused a target point of the living tissues and generates a pressure pulse sufficient to result in cavitation at this target point

公开(公告)号：EP3363498B1

公开(公告)日：2019-12-25

申请号：EP17305179.8

申请日：2017-02-17

申请人： Cardiawave ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  INSERM (Institut National de la Santé et de la Recherche Médicale) ,  Centre National de la Recherche Scientifique (CNRS) ,  Université Paris Diderot - Paris 7

发明人： TANTER, Mickaël ,  PERNOT, Mathieu ,  ROBIN, Justine

IPC分类号： A61N7/00 ,  A61N7/02 ,  A61B17/22 ,  A61B8/08

公开(公告)号：EP3164078A1

公开(公告)日：2017-05-10

申请号：EP15736571.9

申请日：2015-06-29

申请人： Centre National de la Recherche Scientifique (C.N.R.S.) ,  INSERM - Institut National de la Santé et de la Recherche Médicale ,  Université Pierre et Marie Curie (Paris 6) ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  Université Paris Diderot (Paris 7)

发明人： TANTER, Mickaël ,  GENNISSON, Jean-Luc ,  DEFFIEUX, Thomas ,  PERNOT, Mathieu

IPC分类号： A61B8/08 ,  G06T7/00

CPC分类号： A61B8/06 ,  A61B8/0808 ,  A61B8/0891 ,  A61B8/483 ,  A61B8/488 ,  A61B8/5223 ,  A61B8/523 ,  A61B8/5246 ,  G06T7/0016 ,  G06T7/12 ,  G06T7/149 ,  G06T7/174 ,  G06T2207/10072 ,  G06T2207/10136 ,  G06T2207/20128 ,  G06T2207/30016 ,  G06T2207/30104

摘要： Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to be studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (le) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (le) on the vascular image to be studied (IVO).

摘要翻译： 用于脑功能成像的方法，包括以下步骤：（a）通过超声成像对脑进行成像以获得待研究的血管图像（IVO），（b）待研究的血管图像（IVO）为 通过形状识别自动地与脑血管图谱（AV）进行比较，因此待研究的血管图像（IVO）位于脑血管图谱（AV），（c）脑功能图谱（AF） 所述脑血管图谱（AV）并且包括位于该脑血管图谱（AV）中的脑功能区（le）以这样的方式用于识别待研究的血管图像（IVO）上的脑功能区（le）。

公开(公告)号：EP2858760A2

公开(公告)日：2015-04-15

申请号：EP13730033.1

申请日：2013-06-04

申请人： Centre National de la Recherche Scientifique (CNRS) ,  Institut National de la Santé et de la Recherche Médicale (INSERM)

发明人： ARNAL, Bastien ,  PERNOT, Mathieu ,  TANTER, Mickaël ,  FINK, Mathias

IPC分类号： B06B3/04 ,  G10K11/26

CPC分类号： A61N7/00 ,  A61B8/085 ,  A61B17/22004 ,  A61B2017/22008 ,  A61B2017/22015 ,  A61B2017/22028 ,  A61N7/02 ,  A61N2007/0052 ,  A61N2007/006 ,  B06B3/04 ,  G10K11/26 ,  G10K15/00

摘要： Device for focusing pulses comprising at least emitting means comprising a network (5) of transducers (6), these emitting means being adapted to make the network of transducers emit, into a reflective cavity (7), at least one wave focused onto at least one target point (4) of a target medium (2). The reflective cavity comprises a multi—scattering medium (8) adapted to cause multiple scattering of said wave.

摘要翻译： 用于聚焦脉冲的装置包括至少包括发射装置的发射装置，所述发射装置包括一个换能器网络，这些发射装置适于使换能器网络发射到反射腔中，聚焦在目标介质的至少一个目标点上的至少一个波。 反射腔包括适于引起所述波的多次散射的多散射介质。