INORGANIC POROUS CARRIER AND METHOD FOR PRODUCING NUCLEIC ACIDS USING SAME

    公开(公告)号:EP3950126A1

    公开(公告)日:2022-02-09

    申请号:EP20785077.7

    申请日:2020-02-28

    摘要: The present invention provides: an inorganic porous carrier, which can increase yield, etc., in the preparation of nucleic acids, has pore distribution in which a pore diameter (mode diameter) is 0.04 µm or more, and comprises a linker represented by formula (1) [wherein, a bond marked with * represents a bond to an oxygen atom of a silanol group in an inorganic porous substance. R 1 and R 2 represent each independently an alkyl group containing 3 to 10 carbon atoms, or a phenyl group. L represents a single bond; an alkylene group containing 1 to 20 carbon atoms; or an alkylene group containing 2 to 20 carbon atoms which contains -CH 2 -Q-CH 2 -group wherein any group Q selected from a group consisting of -O-, -NH-, -NH-CO-, and -NH-CO-NH- is inserted into at least one of -CH 2 -CH 2 - group constituting the alkylene group. A carbon atom of the methylene group bound to the group Q does not bond to another group Q at the same time.]; and a method for preparing nucleic acids using the same.