公开(公告)号：EP2455097A4

公开(公告)日：2013-02-27

申请号：EP10799943

申请日：2010-07-16

申请人： SUNSTAR INC ,  UNIV HIROSAKI

发明人： GOTO MASASHI ,  YAMAMOTO KAZUSHI ,  KATOU YOUJI ,  KATAGATA YOHTARO ,  ITOU SEIKO

IPC分类号： A61K38/00 ,  A23L1/30 ,  A61K8/73 ,  A61K35/60 ,  A61P17/00 ,  A61P17/16 ,  A61Q11/00 ,  A61Q19/00 ,  C08B37/00

CPC分类号： A61K8/64 ,  A23F3/30 ,  A23G3/36 ,  A23G4/06 ,  A23L29/275 ,  A23L33/17 ,  A23V2002/00 ,  A61K8/735 ,  A61K35/60 ,  A61K2800/92 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/08 ,  C08B37/0066 ,  A23V2200/318 ,  A23V2250/543

摘要： The present invention was made in view of an object to produce a novel proteoglycan-containing material, and find a novel use and/or a superior effect of the proteoglycan-containing material. The present invention provides a proteoglycan-containing material obtained from fish cartilage, wherein the proteoglycan-containing material comprises an acidic saccharide component having a molecular weight of not less than 2000 kDa. The proteoglycan-containing material provides advantageous effects for skin-moisturizing and skin anti-aging, including a superior skin fibroblast proliferation effect, an effect of enhancing and improving the skin barrier function, an effect of enhancing and improving the skin's capability to produce collagen, a dermis-thickening inhibition effect, and the like.

公开(公告)号：EP2666467A4

公开(公告)日：2014-11-19

申请号：EP12737027

申请日：2012-01-19

申请人： UNIV HIROSAKI ,  SUNSTAR INC

发明人： KATO YOJI ,  KATAGATA YOHTARO ,  GOTO MASASHI ,  YAMAMOTO KAZUSHI ,  MAEDA MARIKO ,  HANADA YUKAKO ,  TAKAI MOTOKO ,  SUEKAWA YUTAKA

IPC分类号： A61K35/60 ,  A23L1/30 ,  A23L1/305 ,  A23L2/66 ,  A61K8/64 ,  A61K8/98 ,  A61K38/00 ,  A61K38/01 ,  A61K38/17 ,  A61P17/16 ,  A61P29/00 ,  A61Q19/08 ,  C07K14/46 ,  C07K14/78 ,  C08B37/00

CPC分类号： C07K14/78 ,  A23L2/66 ,  A23L33/10 ,  A23L33/17 ,  A61K8/64 ,  A61K8/987 ,  A61K35/60 ,  A61K38/014 ,  A61K2800/805 ,  A61Q19/08 ,  C07K14/461 ,  C08B37/0066

公开(公告)号：EP2195032A4

公开(公告)日：2012-08-01

申请号：EP08799474

申请日：2008-09-11

申请人： JOSLIN DIABETES CENTER INC ,  SUNSTAR INC

发明人： BLACKWELL T KEITH ,  MATSUMOTO MOTONOBU ,  MAKINO TAKETOSHI ,  GOTO MASASHI ,  ISHIKADO ATSUSHI ,  MAEDA MARIKO ,  AZECHI SATOE

IPC分类号： A61K47/00 ,  A61K36/76 ,  A61P17/18

CPC分类号： A61K36/76 ,  G01N33/5014 ,  G01N2500/10

摘要： Provided are methods and compositions that enhance Nrf2 (SKN-1) activation of phase II detoxification or antioxidant enzyme transcription, comprising plant extracts (e.g., willow extracts) or active fractions thereof, as well as methods for identifying additional compounds that increase the Nrf2-regulation of those enzymes.