专利检索 ap:("Samyang Genex Corporation") AND inv:"LEE, Sa-Won Daerimdoorae Apt." 第 1 页

1.

发明公开
DELIVERY SYSTEM FOR BIOACTIVE AGENTS ON THE BASIS OF A POLYMERIC DRUG CARRIER COMPRISING AN AMPHIPHILIC BLOCK POLYMER AND A POLYLACTICACID DERIVATIVE 有权
标题翻译：供给系统为基础的药物载体与AMPIPHILEN嵌段聚合物聚合物的生物有效的手段的聚乳酸衍生物

公开(公告)号：EP1742665A1

公开(公告)日：2007-01-17

申请号：EP05739818.2

申请日：2005-05-06

申请人： Samyang Genex Corporation

发明人： YI, Yil-Woong , LEE, Sa-Won Daerimdoorae Apt. , YU, Jeong-Il , CHANG, Dong-Hoon , SEO, Min-Hyo , KANG, Hye-Won , KIM, Jae-Hong

IPC分类号： A61K47/34 , C08G63/91

CPC分类号： C08G63/912 , A61K9/0019 , A61K9/1075 , A61K9/19 , A61K9/5153 , A61K47/34 , C08G2261/126 , C08L53/00 , C08L67/00 , C08L67/04 , C08L87/005 , C08L101/06 , C08L2666/02

摘要： Delivery system for bioactive agents on the basis of a polymeric drug carrier formed from compositions comprising an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block having a terminal hydroxyl group substituted with a tocopherol or cholesterol group, and a polylactic acide derivative wherein one end of the polylactic acid is covalently bound to at least one carboxyl group. The carboxyl group of the polylactic acid derivative may be fixed with a di- or trivalent metal ion,which is obtained by adding the di- or trivalent metal ion to the polymeric composition.