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公开(公告)号:EP3492593A1
公开(公告)日:2019-06-05
申请号:EP18214711.6
申请日:2014-11-13
发明人: ORKIN, Stuart H. , REIK, Andreas , URNOV, Fyodor
IPC分类号: C12N15/09 , A61K38/46 , A61P7/00 , A61K35/12 , A61K35/28 , C07K14/47 , C12N9/22 , C12N15/113
摘要: The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a hematopoietic cell.
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公开(公告)号:EP3068881B1
公开(公告)日:2019-02-27
申请号:EP14861930.7
申请日:2014-11-13
发明人: ORKIN, Stuart H. , REIK, Andreas , URNOV, Fyodor
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公开(公告)号:EP3311822A1
公开(公告)日:2018-04-25
申请号:EP17205646.7
申请日:2011-11-17
发明人: GREGORY, Philip D. , HOLMES, Michael C. , MENDEL, Matthew C. , MENG, Xiangdong , PASCHON, David , REIK, Andreas , URNOV, Fyodor
IPC分类号: A61K31/7088 , C07K14/435 , C07H21/00 , C12N5/0783 , A61P35/00 , A61P31/12 , C12N9/22 , A61K38/17 , A61K35/17
摘要: Disclosed herein are methods and compositions for modulating expression of a PD1 gene.
摘要翻译: 本文公开了用于调节PD1基因表达的方法和组合物。
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公开(公告)号:EP4347810A2
公开(公告)日:2024-04-10
申请号:EP22811985.5
申请日:2022-05-24
发明人: ZHANG, Lei , REIK, Andreas
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公开(公告)号:EP3960856A1
公开(公告)日:2022-03-02
申请号:EP21187166.0
申请日:2014-11-13
发明人: ORKIN, Stuart H. , REIK, Andreas , URNOV, Fyodor
IPC分类号: C12N15/09 , A61K38/46 , A61P7/00 , A61K35/12 , A61K35/28 , C07K14/47 , C12N9/22 , C12N15/113
摘要: The present disclosure is in the field of genome engineering, particularly targeted modification of the genome of a hematopoietic cell.
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公开(公告)号:EP3102673B1
公开(公告)日:2020-04-15
申请号:EP15742584.4
申请日:2015-02-02
发明人: LIU, Pei-Qi , REIK, Andreas , ZHANG, Lei
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公开(公告)号:EP3311822B1
公开(公告)日:2020-05-13
申请号:EP17205646.7
申请日:2011-11-17
发明人: GREGORY, Philip D. , HOLMES, Michael C. , MENDEL, Matthew C. , MENG, Xiangdong , PASCHON, David , REIK, Andreas , URNOV, Fyodor
IPC分类号: A61K31/7088 , C07K14/435 , C07H21/00 , C12N5/0783 , A61P35/00 , A61P31/12 , C12N9/22 , A61K38/17 , A61K35/17
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公开(公告)号:EP2640399B1
公开(公告)日:2017-12-20
申请号:EP11840913.5
申请日:2011-11-17
发明人: GREGORY, Philip D. , HOLMES, Michael C. , MENDEL, Matthew C. , MENG, Xiangdong , PASCHON, David , REIK, Andreas , URNOV, Fyodor
IPC分类号: A61K31/7088 , C07K14/435 , C07H21/00 , C12N5/0783 , A61P35/00 , A61P31/12 , C12N9/22 , A61K38/17
CPC分类号: A61K38/1709 , A61K35/17 , A61P31/12 , A61P35/00 , C07K2319/71 , C12N9/22
摘要: Disclosed herein are methods and compositions for modulating expression of a PD1 gene.
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公开(公告)号:EP3730615A2
公开(公告)日:2020-10-28
申请号:EP20173697.2
申请日:2014-05-15
发明人: CONWAY, Anthony , COST, Gregory J. , DEKELVER, Russell , REBAR, Edward J. , REIK, Andreas , URNOV, Fyodor , WANG, Jianbin , ZHANG, H. Steve
IPC分类号: C12N15/11 , C12N9/22 , C12N15/90 , C12N15/63 , C07K14/805
摘要: Methods and compositions for genetic alteration of cells are provided
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公开(公告)号:EP3034084B1
公开(公告)日:2018-08-01
申请号:EP16150673.8
申请日:2011-11-17
发明人: GREGORY, Philip D. , HOLMES, Michael C. , MENDEL, Matthew C. , MENG, Xiangdong , PASCHON, David , REIK, Andreas , URNOV, Fyodor
IPC分类号: A61K31/7088 , C07K14/435 , C07H21/00 , C12N5/0783 , A61P35/00 , A61P31/12 , C12N9/22 , A61K38/17 , A61K35/17
CPC分类号: A61K38/1709 , A61K35/17 , A61P31/12 , A61P35/00 , C07K2319/71 , C12N9/22 , Y02A50/463
摘要: Disclosed herein are methods and compositions for modulating expression of a PD1 gene.
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