公开(公告)号：EP2515940A1

公开(公告)日：2012-10-31

申请号：EP10838455.3

申请日：2010-12-20

申请人： Sanofi Pasteur Limited

发明人： HARPER, Kevin ,  LJUTIC, Belma ,  GALLICHAN, Scott ,  OCHS, Martina, Ochs ,  MOREFIELD, Garry ,  SALHA, Marie-Danielle ,  AUSAR, Fernando

IPC分类号： A61K39/39 ,  A61K39/02 ,  A61K39/09 ,  A61P31/04 ,  A61P37/04

CPC分类号： A61K39/39 ,  A61K9/0019 ,  A61K39/092 ,  A61K47/26 ,  A61K2039/55505

摘要： This disclosure relates to adjuvants for use in immunogenic compositions comprising at least one antigen and an aluminum compound comprising hydroxyl groups that has been treated with phosphate, carboxylate, carbonate, sulfate diphosphonate or a mixture of two or more of these compounds and methods of using these compositions for preventing and treating diseases are also provided.

公开(公告)号：EP2515938A1

公开(公告)日：2012-10-31

申请号：EP10838456.1

申请日：2010-12-20

申请人： Sanofi Pasteur Limited

发明人： GALLICHAN, Scott ,  HARPER, Kevin ,  LJUTIC, Belma ,  OCHS, Martina, Ochs ,  MOREFIELD, Garry ,  AUSAR, Fernando ,  SALHA, Marie-Danielle

IPC分类号： A61K39/09 ,  A61P31/04 ,  A61P37/04

CPC分类号： A61K39/092 ,  A61K2039/55505 ,  C07K16/1275

摘要： This disclosure relates to immunogenic compositions comprising an isolated immunogenic
S. pneumoniae PcpA polypeptide and at least one additional antigen (such as for example, an isolated immunogenic
S. pneumoniae polypeptide selected from the group consisting of the polyhistidine triad family of proteins (e g. PhtD) and methods of using these compositions for preventing and treating diseases caused by
S. pneumoniae.