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1.发明授权Substituierte 8-Aminoalkoxixanthine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel 有权取代的8- Aminoalkoxixanthine，它们的制备方法和它们作为药物的用途
公开(公告)号：EP1778690B1
公开(公告)日：2012-08-22
申请号：EP05770568.3
申请日：2005-07-30
发明人： SCHOENAFINGER, Karl , JAEHNE, Gerhard , DEFOSSA, Elisabeth , BUNING, Christian , TSCHANK, Georg , WERNER, Ulrich
IPC分类号： C07D473/08 , A61K31/522 , A61P3/10
CPC分类号： C07D473/04
摘要： The invention relates to substituted 8-aminoalkoxi-xanthines and to the physiologically compatible salts thereof and physiologically functional derivatives. The invention also relates to compounds of formula (I), wherein the radicals have the above-mentioned meaning, in addition to the physiologically compatible salts thereof. The compounds are suitable, for example, as medicaments for the prevention and treatment of type 2 diabetes.
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2.发明授权C2-SUBSTITUIERTE INDAN-1-ONE UND IHRE DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权C2-取代茚-1-酮及其衍生物，用于生产及其作为药物
公开(公告)号：EP1425267B1
公开(公告)日：2010-06-30
申请号：EP02769973.5
申请日：2002-08-17
IPC分类号： C07C317/24 , C07C323/22 , A61K31/10 , A61P3/04
CPC分类号： C07C317/24 , C07C323/22 , C07C2602/08
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3.发明授权NEUES DIPHENYLAZETIDINON MIT VERBESSERTEN PHYSIOLOGISCHEN EIGENSCHAFTEN, VERFAHREN ZU DESSEN HERSTELLUNG, DIESE VERBINDUNG ENTHALTENDE ARZNEIMITTEL UND DESSEN VERWENDUNG 有权具有改进的生理特性NEW diphenylazetidinone，生产工艺为那些相关的药物含及其用途
公开(公告)号：EP1613589B1
公开(公告)日：2008-02-13
申请号：EP04720854.1
申请日：2004-03-16
发明人： JAEHNE, Gerhard , FRICK, Wendelin , LINDENSCHMIDT, Andreas , FLOHR, Stefanie , HEUER, Hubert , SCHAEFER, Hans-Ludwig , KRAMER, Werner , GALIA, Eric , GLOMBIK, Heiner
IPC分类号： C07D205/08 , A61K31/397 , A61P3/06
CPC分类号： C07C233/18 , C07D205/08
摘要： The invention relates to a novel diphenyl azetidinone, to a method for its production, to medicaments containing said compound and to the use of the latter. The invention relates to the compound of general formula (I), in addition to its physiologically compatible salts. Said compound is suitable for use for example as a hypolipidaemic agent.
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4.发明公开SUBSTITUIERTE, BISZYKLISCHE 8-PYRROLIDINO-XANTHINE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 审中-公开取代，BISZYKLISCHE 8吡咯烷子黄嘌呤，其制造方法相同，它们作为药物
公开(公告)号：EP1776372A1
公开(公告)日：2007-04-25
申请号：EP05774377.5
申请日：2005-07-22
发明人： SCHOENAFINGER, Karl , JAEHNE, Gerhard , DEFOSSA, Elisabeth , SCHWINK, Lothar , WAGNER, Holger , BUNING, Christian , TSCHANK, Georg , WERNER, Ulrich
IPC分类号： C07D519/00 , A61K31/522
CPC分类号： C07D519/00
摘要： The invention relates to substituted, bicyclic 8-aminoxanthines, their physiologically compatible salts and to their physiologically functional derivatives. The invention relates to compounds of formula (I), in which the radicals have the cited meanings, and to their physiologically compatible salts. The compounds are suited, e.g. for use as medicaments for preventing and treating type 2 diabetes.
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5.发明公开NEUE CYANOTHIAZOLIDE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权新CYANOTHIAZOLIDE，其制造方法相同，它们作为药物
公开(公告)号：EP1651653A1
公开(公告)日：2006-05-03
申请号：EP04740985.9
申请日：2004-07-14
发明人： WAGNER, Holger , SCHOENAFINGER, Karl , JAEHNE, Gerhard , GAUL, Holger , BUNING, Christian , TSCHANK, Georg , WERNER, Ulrich
IPC分类号： C07D513/04 , A61K31/415
CPC分类号： C07D487/04
摘要： The invention relates to compounds of formula (I), wherein the radicals have the meanings indicated in the text, the stereoisomeric forms thereof, the physiologically acceptable salts thereof, and methods for the production thereof. The inventive compounds are suitable for the treatment of metabolic diseases such as type 2 diabetes.
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6.发明授权NEUE CYANOTHIAZOLIDE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权新CYANOTHIAZOLIDE，其制造方法相同，它们作为药物
公开(公告)号：EP1651653B1
公开(公告)日：2011-11-23
申请号：EP04740985.9
申请日：2004-07-14
发明人： WAGNER, Holger , SCHOENAFINGER, Karl , JAEHNE, Gerhard , GAUL, Holger , BUNING, Christian , TSCHANK, Georg , WERNER, Ulrich
IPC分类号： C07D513/04 , A61K31/415
CPC分类号： C07D487/04
摘要： The invention relates to compounds of formula (I), wherein the radicals have the meanings indicated in the text, the stereoisomeric forms thereof, the physiologically acceptable salts thereof, and methods for the production thereof. The inventive compounds are suitable for the treatment of metabolic diseases such as type 2 diabetes.
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公开(公告)号：EP1530568B1
公开(公告)日：2010-12-29
申请号：EP03793685.3
申请日：2003-08-05
发明人： RITZELER, Olaf , JAEHNE, Gerhard
IPC分类号： C07D401/14 , C07D403/12
CPC分类号： C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14 , C07D417/04
摘要： The invention relates to compounds of formula (I). Said compounds are suitable for producing medicaments for the prophylaxis and treatment of diseases, the progression of which involves increased activity of IκB kinase.
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8.发明授权MEHRFACH SUBSTITUIERTE INDAN-1-OL-SYSTEME, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权多取代茚-1-醇系统，其制造方法相同，它们作为药物
公开(公告)号：EP1423358B1
公开(公告)日：2010-08-04
申请号：EP02764854.2
申请日：2002-08-17
IPC分类号： C07C317/20 , C07C323/17 , A61K31/10 , A61P3/04
CPC分类号： C07C323/17 , C07C317/20 , C07C2602/08
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公开(公告)号：EP1345932B1
公开(公告)日：2006-10-18
申请号：EP01271371.5
申请日：2001-12-11
发明人： GLOMBIK, Heiner , KRAMER, Werner , FLOHR, Stefanie , FRICK, Wendelin , HEUER, Hubert , JAEHNE, Gerhard , LINDENSCHMIDT, Andreas , SCHAEFER, Hans-Ludwig
IPC分类号： C07D409/12 , A61K31/397 , A61P9/00
CPC分类号： C07D401/14 , C07D205/08 , C07D409/12
摘要： The invention relates to novel diphenyl azetidinones, to a method for the production thereof, to medicaments containing these compounds, and to their use. The invention concerns compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 have the cited meanings, and concerns the physiologically compatible salts thereof. The compounds are suited for use e.g. as hypolipidemic drugs.
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10.发明授权DIPHENYLAZETIDINONDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权DIPHENYLAZETIDINONDERIVATE，方法及其，药品含有它们及其用途
公开(公告)号：EP1345924B1
公开(公告)日：2006-08-30
申请号：EP01991821.8
申请日：2001-12-11
发明人： GLOMBIK, Heiner , KRAMER, Werner , FLOHR, Stefanie , FRICK, Wendelin , HEUER, Hubert , JAEHNE, Gerhard , LINDENSCHMIDT, Andreas , SCHAEFER, Hans-Ludwig
IPC分类号： C07D401/14 , A61K31/444 , A61P9/10
CPC分类号： C07D401/14 , C07D205/08 , C07D409/12
摘要： The invention relates to novel diphenyl azetidinones, to a method for the production thereof, to medicaments containing these compounds, and to their use. The invention concerns compounds of formula (I), wherein R1, R2, R3, R4, R5 and R6 have the cited meanings, and concerns the physiologically compatible salts thereof. The compounds are suited for use e.g. as hypolipidemic drugs.
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