公开(公告)号：EP2943495A1

公开(公告)日：2015-11-18

申请号：EP14703275.9

申请日：2014-01-07

申请人： Savira Pharmaceuticals GmbH ,  F. Hoffmann-La Roche AG ,  European Molecular Biology Laboratory

发明人： Wolkerstorfer, Andrea ,  Szolar, Oliver ,  Handler, Norbert ,  Buschmann, Helmut ,  Cusack, Stephen ,  Smith, Mark ,  So, Sung-Sau ,  Hawley, Ronald Charles ,  Sidduri, Achyutharao ,  Zhang, Zhuming

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61P31/12

CPC分类号： C07D487/04 ,  A61K31/519 ,  A61K45/06 ,  C07D403/04 ,  C07D471/04

摘要： The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph,codrug, cocrystal,prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.

公开(公告)号：EP2943495B1

公开(公告)日：2016-12-28

申请号：EP14703275.9

申请日：2014-01-07

申请人： Savira Pharmaceuticals GmbH ,  F. Hoffmann-La Roche AG ,  European Molecular Biology Laboratory

发明人： Wolkerstorfer, Andrea ,  Szolar, Oliver ,  Handler, Norbert ,  Buschmann, Helmut ,  Cusack, Stephen ,  Smith, Mark ,  So, Sung-Sau ,  Hawley, Ronald Charles ,  Sidduri, Achyutharao ,  Zhang, Zhuming

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61P31/12

CPC分类号： C07D487/04 ,  A61K31/519 ,  A61K45/06 ,  C07D403/04 ,  C07D471/04