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公开(公告)号:EP2350072A1
公开(公告)日:2011-08-03
申请号:EP09748190.7
申请日:2009-10-26
申请人: Schering Corporation
发明人: HO, Ginny D , YANG, Shu-Wei , SMITH, Elizabeth M , MCELROY, William Thomas , BASU, Kallol , SMOTRYSKI, Jennifer , TAN, Zheng , MCKITTRICK, Brian A. , TULSHIAN, Deen B.
IPC分类号: C07D471/04 , C07D491/113 , A61K31/4439 , A61P25/18
CPC分类号: C07D471/04 , C07D491/113
摘要: The present invention relates to substituted pyrazoloquinolines of formula I and derivatives thereof, the use of the compounds as phosphodiesterase 10 (PDElO) inhibitors for the treatment of PDElO -modulated disorders, to pharmaceutical compositions comprising the compounds, and to the use of additional substituted pyrazoloquinolines and derivatives thereof for the treatment of PDElO -modulated disorders.