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1.发明公开3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS 有权3,4-二取代的环丁烯-1,2-二酮ALS CXC趋化因子受体配体
公开(公告)号：EP1381590A1
公开(公告)日：2004-01-21
申请号：EP02739172.1
申请日：2002-04-15
发明人： TAVERAS, Arthur, G. , AKI, Cynthia, J. , BOND, Richard, W. , CHAO, Jianping , DWYER, Michael , FERREIRA, Johan, A. , CHAO, Jianhua , YU, Younong , BALDWIN, John, J. , KAISER, Bernd , LI, Ge , MERRITT, J., Robert , NELSON, Kingsley, H. , ROKOSZ, Laura, L.
IPC分类号： C07C237/30 , C07C255/59 , C07C225/20 , C07D213/74 , C07D307/52 , C07D333/36
CPC分类号： C07D231/38 , C07C225/20 , C07C237/30 , C07C255/59 , C07C2601/04 , C07D213/74 , C07D307/52 , C07D333/36
摘要： There are disclosed compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
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2.发明授权3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS 有权3,4-DISUBSTITUIERTE CYCLOBUTEN-1,2-DIONE ALS CXC-CHEMOKINREZEPTORLIGANDEN
公开(公告)号：EP1381590B1
公开(公告)日：2007-06-20
申请号：EP02739172.1
申请日：2002-04-15
发明人： TAVERAS, Arthur, G. , AKI, Cynthia, J. , BOND, Richard, W. , CHAO, Jianping , DWYER, Michael , FERREIRA, Johan, A. , CHAO, Jianhua , YU, Younong , BALDWIN, John, J. , KAISER, Bernd , LI, Ge , MERRITT, J., Robert , NELSON, Kingsley, H. , ROKOSZ, Laura, L.
IPC分类号： C07C237/30 , C07C255/59 , C07C225/20 , C07D213/74 , C07D307/52 , C07D333/36
CPC分类号： C07D231/38 , C07C225/20 , C07C237/30 , C07C255/59 , C07C2601/04 , C07D213/74 , C07D307/52 , C07D333/36
摘要： There are disclosed compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
摘要翻译： 公开了可用于治疗趋化因子介导的疾病如急性和慢性炎症性疾病和癌症的具有下式的化合物或其药学上可接受的盐或溶剂合物。
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